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Open AccessReview

Epidemiology and Clinical Characteristics of Influenza C Virus

1
Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
2
Institute for Infection, Inflammation, and Immunity in Children (i4Kids), University of Pittsburgh, Pittsburgh, PA 15224, USA
*
Author to whom correspondence should be addressed.
Viruses 2020, 12(1), 89; https://doi.org/10.3390/v12010089
Received: 30 December 2019 / Revised: 6 January 2020 / Accepted: 7 January 2020 / Published: 13 January 2020
(This article belongs to the Special Issue Non-A Influenza)
Influenza C virus (ICV) is a common yet under-recognized cause of acute respiratory illness. ICV seropositivity has been found to be as high as 90% by 7–10 years of age, suggesting that most people are exposed to ICV at least once during childhood. Due to difficulty detecting ICV by cell culture, epidemiologic studies of ICV likely have underestimated the burden of ICV infection and disease. Recent development of highly sensitive RT-PCR has facilitated epidemiologic studies that provide further insights into the prevalence, seasonality, and course of ICV infection. In this review, we summarize the epidemiology and clinical characteristics of ICV. View Full-Text
Keywords: orthomyxoviruses; influenza C; epidemiology orthomyxoviruses; influenza C; epidemiology
MDPI and ACS Style

Sederdahl, B.K.; Williams, J.V. Epidemiology and Clinical Characteristics of Influenza C Virus. Viruses 2020, 12, 89.

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