Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?
Abstract
:1. Introduction
2. Viruses as Plausible Etiologic Agents in Neurological Disorders
3. Respiratory Viruses with Neuroinvasive and Neurotropic Properties: Possible Associated Neuropathologies
4. Human Coronaviruses: Eclosions of Recognized Respiratory Pathogens
4.1. Human Coronaviruses: Pathogens Causing Illnesses Outside the Respiratory Tract
4.1.1. Possible Mechanisms of HCoV Neuroinvasiveness
4.1.2. Human Coronaviruses in the CNS: Possible Associated Neurological Pathologies
Potential Short-Term Neuropathologies
Potential Long-Term Neuropathologies and Sequelae
4.1.3. Mechanisms of HCoV-Induced Neurodegeneration: Possible Associated Neuropathologies
5. Conclusions
Funding
Acknowledgments
Conflicts of Interest
References
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Desforges, M.; Le Coupanec, A.; Dubeau, P.; Bourgouin, A.; Lajoie, L.; Dubé, M.; Talbot, P.J. Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? Viruses 2020, 12, 14. https://doi.org/10.3390/v12010014
Desforges M, Le Coupanec A, Dubeau P, Bourgouin A, Lajoie L, Dubé M, Talbot PJ. Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? Viruses. 2020; 12(1):14. https://doi.org/10.3390/v12010014
Chicago/Turabian StyleDesforges, Marc, Alain Le Coupanec, Philippe Dubeau, Andréanne Bourgouin, Louise Lajoie, Mathieu Dubé, and Pierre J. Talbot. 2020. "Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?" Viruses 12, no. 1: 14. https://doi.org/10.3390/v12010014