Next Article in Journal
Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?
Previous Article in Journal
The Zebrafish Xenograft Platform—A Novel Tool for Modeling KSHV-Associated Diseases
Open AccessArticle

Three New Orbivirus Species Isolated from Farmed White-Tailed Deer (Odocoileus virginianus) in the United States

1
Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
2
Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA
3
Faculty of Veterinary and Animal Sciences, Hajee Mohammad Danesh Science and Technology University, Dinajpur 5200, Rangpur, Bangladesh
4
Department of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611-0430, USA
5
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA
6
Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL 32610-0188, USA
7
Center for Biodefense and Emerging Infectious Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, TX 77555-0609, USA
8
Unité des Virus Emergents (UVE: Aix-Marseille Univ, IRD 190, INSERM U1207, IHU Méditerranée Infection), Aix Marseille Universite, 13000 Marseille, France
*
Author to whom correspondence should be addressed.
Present address: Biological Consulting Services of North Florida., Gainesville, FL 32609, USA.
Viruses 2020, 12(1), 13; https://doi.org/10.3390/v12010013
Received: 23 November 2019 / Revised: 13 December 2019 / Accepted: 17 December 2019 / Published: 20 December 2019
(This article belongs to the Section Animal Viruses)
We report the detection and gene coding sequences of three novel Orbivirus species found in six dead farmed white-tailed deer in the United States. Phylogenetic analyses indicate that the new orbiviruses are genetically closely related to the Guangxi, Mobuck, Peruvian horse sickness, and Yunnan orbiviruses, which are thought to be solely borne by mosquitos. However, four of the six viruses analyzed in this work were found as co-infecting agents along with a known cervid pathogen, epizootic hemorrhagic disease virus-2 (EHDV-2), raising questions as to whether the new viruses are primary pathogens or secondary pathogens that exacerbate EHDV-2 infections. Moreover, EHDV-2 is known to be a Culicoides-borne virus, raising additional questions as to whether Culicoides species can also serve as vectors for the novel orbiviruses, if mosquitoes can vector EHDV-2, or whether the deer were infected through separate bites by the insects. Our findings expand knowledge of the possible viral pathogens of deer in the United States. Moreover, due to the close genetic relatedness of the three new orbiviruses to viruses that are primary pathogens of cattle and horses, our findings also underscore a crucial need for additional research on the potential role of the three new orbiviruses as pathogens of other animals. View Full-Text
Keywords: deer farming; Odocoileus virginianus; orbivirus; reovirus; white-tailed deer deer farming; Odocoileus virginianus; orbivirus; reovirus; white-tailed deer
Show Figures

Figure 1

MDPI and ACS Style

Ahasan, M.S.; Subramaniam, K.; Campos Krauer, J.M.; Sayler, K.A.; Loeb, J.C.; Goodfriend, O.F.; Barber, H.M.; Stephenson, C.J.; Popov, V.L.; Charrel, R.N.; Wisely, S.M.; Waltzek, T.B.; Lednicky, J.A. Three New Orbivirus Species Isolated from Farmed White-Tailed Deer (Odocoileus virginianus) in the United States. Viruses 2020, 12, 13. https://doi.org/10.3390/v12010013

AMA Style

Ahasan MS, Subramaniam K, Campos Krauer JM, Sayler KA, Loeb JC, Goodfriend OF, Barber HM, Stephenson CJ, Popov VL, Charrel RN, Wisely SM, Waltzek TB, Lednicky JA. Three New Orbivirus Species Isolated from Farmed White-Tailed Deer (Odocoileus virginianus) in the United States. Viruses. 2020; 12(1):13. https://doi.org/10.3390/v12010013

Chicago/Turabian Style

Ahasan, Mohammad S.; Subramaniam, Kuttichantran; Campos Krauer, Juan M.; Sayler, Katherine A.; Loeb, Julia C.; Goodfriend, Olivia F.; Barber, Hannah M.; Stephenson, Caroline J.; Popov, Vsevolod L.; Charrel, Remi N.; Wisely, Samantha M.; Waltzek, Thomas B.; Lednicky, John A. 2020. "Three New Orbivirus Species Isolated from Farmed White-Tailed Deer (Odocoileus virginianus) in the United States" Viruses 12, no. 1: 13. https://doi.org/10.3390/v12010013

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop