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Open AccessArticle

Tissue-Like Phantoms as a Platform for Inserted Fluorescence Nano-Probes

Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel
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Academic Editor: Zeev Zalevsky
Materials 2016, 9(11), 926; https://doi.org/10.3390/ma9110926
Received: 19 September 2016 / Revised: 26 October 2016 / Accepted: 9 November 2016 / Published: 15 November 2016
(This article belongs to the Special Issue Nanoprobes for Imaging)
Tissue-like phantoms are widely used as a model for mimicking the optical properties of live tissue. This paper presents the results of a diffusion reflection method and fluorescence lifetime imaging microscopy measurements of fluorescein-conjugated gold nanorods in solution, as well as inserted in solid tissue-imitating phantoms. A lack of consistency between the fluorescence lifetime results of the solutions and the phantoms raises a question about the ability of tissue-like phantoms to maintain the optical properties of inserted contrast agents. View Full-Text
Keywords: tissue-like phantoms; dual-modal imaging; fluorescence lifetime (FLT); FLT imaging (FLIM); diffusion reflection tissue-like phantoms; dual-modal imaging; fluorescence lifetime (FLT); FLT imaging (FLIM); diffusion reflection
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MDPI and ACS Style

Nayhoz, T.; Barnoy, E.A.; Fixler, D. Tissue-Like Phantoms as a Platform for Inserted Fluorescence Nano-Probes. Materials 2016, 9, 926.

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