Characterization of a Toothpaste Containing Bioactive Hydroxyapatites and In Vitro Evaluation of Its Efficacy to Remineralize Enamel and to Occlude Dentinal Tubules
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Sample Preparation
2.3. Structural Characterization
2.4. Compositional Analysis
2.5. In Vitro Evaluation of Remineralization and Dentinal Tubules Occlusion
2.6. Statistical Analysis
3. Results and Discussion
3.1. Structural Characterization
3.2. Compositional Analysis
3.3. In Vitro Evaluation of Remineralization
3.4. In Vitro Evaluation of Dentinal Tubules Occlusion
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Commercial Name | Ingredients |
---|---|
Biosmalto Caries Abrasion and Erosion | Purified water, glycerin, hydrated silica, fluorohydroxyapatite, magnesium-strontium-carbonate-hydroxyapatite conjugated with chitosan, cellulose gum, xylitol, cocamidopropyl betaine, xantham gum, aroma, sodium monofluorophosphate, potassium acesulfame, ethylhexylglicerin, phenoxyethanol, sodium benzoate, citric acid. |
Sample | Si (wt%) a | Ca (wt%) a | P (wt%) a | Mg (wt%) a | Sr (wt%) a | F (ppm) b | Ca/P (mol) a |
---|---|---|---|---|---|---|---|
Whole toothpaste | 3.5 ± 0.1 | 1.1 ± 0.1 | 0.8 ± 0.1 | 0.02 ± 0.01 | 0.09 ± 0.01 | 1458 ± 25 | 0.96 ± 0.05 |
Water-insoluble fraction | 29.8 ± 1.9 | 9.2 ± 0.3 | 4.6 ± 0.2 | 0.20 ± 0.01 | 0.72 ± 0.01 | 1390 ± 25 | 1.51 ± 0.01 |
Sample | Si (wt%) | Ca (wt%) | P (wt%) | Mg (wt%) | Sr (wt%) | F (wt%) | Ca/P (mol) |
---|---|---|---|---|---|---|---|
Enamel, control | 0.07 ± 0.01 | 37.9 ± 0.1 | 16.4 ± 0.1 | 0.3 ± 0.1 | - | - | 1.79 ± 0.01 |
Enamel, treated | 1.2 ± 0.1 | 35.4 ± 0.1 | 14.5 ± 0.1 | 0.2 ± 0.1 | 0.3 ± 0.1 | 0.22 ± 0.05 | 1.89 ± 0.01 |
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Degli Esposti, L.; Ionescu, A.C.; Brambilla, E.; Tampieri, A.; Iafisco, M. Characterization of a Toothpaste Containing Bioactive Hydroxyapatites and In Vitro Evaluation of Its Efficacy to Remineralize Enamel and to Occlude Dentinal Tubules. Materials 2020, 13, 2928. https://doi.org/10.3390/ma13132928
Degli Esposti L, Ionescu AC, Brambilla E, Tampieri A, Iafisco M. Characterization of a Toothpaste Containing Bioactive Hydroxyapatites and In Vitro Evaluation of Its Efficacy to Remineralize Enamel and to Occlude Dentinal Tubules. Materials. 2020; 13(13):2928. https://doi.org/10.3390/ma13132928
Chicago/Turabian StyleDegli Esposti, Lorenzo, Andrei C. Ionescu, Eugenio Brambilla, Anna Tampieri, and Michele Iafisco. 2020. "Characterization of a Toothpaste Containing Bioactive Hydroxyapatites and In Vitro Evaluation of Its Efficacy to Remineralize Enamel and to Occlude Dentinal Tubules" Materials 13, no. 13: 2928. https://doi.org/10.3390/ma13132928