Next Article in Journal
A Parasitic Resistance-Adapted Programming Scheme for Memristor Crossbar-Based Neuromorphic Computing Systems
Next Article in Special Issue
Magnetic and Golden Yogurts. Food as a Potential Nanomedicine Carrier
Previous Article in Journal
Atom Probe Tomography Analysis of TiCx Powders Synthesized by SHS in Al/Fe/Cu–Ti–C Systems
Previous Article in Special Issue
Understanding the Influence of a Bifunctional Polyethylene Glycol Derivative in Protein Corona Formation around Iron Oxide Nanoparticles
Open AccessReview

Magnetic Nanoparticles Supporting Bio-responsive T1/T2 Magnetic Resonance Imaging

Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QZ, UK
*
Author to whom correspondence should be addressed.
Materials 2019, 12(24), 4096; https://doi.org/10.3390/ma12244096
Received: 12 November 2019 / Revised: 29 November 2019 / Accepted: 2 December 2019 / Published: 7 December 2019
(This article belongs to the Special Issue Nanoparticles for Biomedical Applications)
The use of nanoparticulate systems as contrast agents for magnetic resonance imaging (MRI) is well-established and known to facilitate an enhanced image sensitivity within scans of a particular pathological region of interest. Such a capability can enable both a non-invasive diagnosis and the monitoring of disease progression/response to treatment. In this review, magnetic nanoparticles that exhibit a bio-responsive MR relaxivity are discussed, with pH-, enzyme-, biomolecular-, and protein-responsive systems considered. The ability of a contrast agent to respond to a biological stimulus provides not only enriched diagnostic capabilities over corresponding non-responsive analogues, but also an improved longitudinal monitoring of specific physiological conditions. View Full-Text
Keywords: Bio-responsive; Nanoparticle; pH-responsive; Enzyme-responsive; Biomolecule-responsive; Magnetic Resonance Imaging; Diagnosis; Therapy; Mesoporous Silica Nanoparticles; Iron Oxide Nanoparticles Bio-responsive; Nanoparticle; pH-responsive; Enzyme-responsive; Biomolecule-responsive; Magnetic Resonance Imaging; Diagnosis; Therapy; Mesoporous Silica Nanoparticles; Iron Oxide Nanoparticles
Show Figures

Figure 1

MDPI and ACS Style

Ellis, C.M.; Pellico, J.; Davis, J.J. Magnetic Nanoparticles Supporting Bio-responsive T1/T2 Magnetic Resonance Imaging. Materials 2019, 12, 4096.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop