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Case Report

A Didactic Case of Long QT Associated with Pheochromocytoma

Cardiology Department, University and Hospital Fribourg, Chemin des Pensionnats 2-6, CH 1708 Fribourg, Switzerland
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Author to whom correspondence should be addressed.
Cardiovasc. Med. 2025, 28(1), 6; https://doi.org/10.3390/cardiovascmed28010006
Submission received: 29 October 2025 / Revised: 26 November 2025 / Accepted: 9 December 2025 / Published: 11 December 2025

Abstract

Long QT associated with pheochromocytoma is rare but clinically significant. A 43-year-old woman presented with palpitations, chest pain, and recurrent syncope. ECG showed ST-segment elevation, while coronary angiography revealed normal arteries but Takotsubo-like left ventricular dysfunction. Hypertension and tachycardia raised suspicion for pheochromocytoma, later confirmed by imaging and biochemical tests. The patient exhibited QT prolongation (QTc 570 ms) in parallel with Takotsubo episodes. Following adrenalectomy, both QT duration and ventricular function normalized. The European Society of Cardiology now classifies pheochromocytoma-induced cardiomyopathy within the Takotsubo spectrum. Early recognition is crucial due to the risk of sudden cardiac death.
Keywords: pheochromocytoma; acquired long QT syndrome; catecholamine-induced cardiomyopathy; Takotsubo syndrome; ECG abnormalities pheochromocytoma; acquired long QT syndrome; catecholamine-induced cardiomyopathy; Takotsubo syndrome; ECG abnormalities

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MDPI and ACS Style

Cook, S.T.; Cook, M. A Didactic Case of Long QT Associated with Pheochromocytoma. Cardiovasc. Med. 2025, 28, 6. https://doi.org/10.3390/cardiovascmed28010006

AMA Style

Cook ST, Cook M. A Didactic Case of Long QT Associated with Pheochromocytoma. Cardiovascular Medicine. 2025; 28(1):6. https://doi.org/10.3390/cardiovascmed28010006

Chicago/Turabian Style

Cook, Selma T., and Malica Cook. 2025. "A Didactic Case of Long QT Associated with Pheochromocytoma" Cardiovascular Medicine 28, no. 1: 6. https://doi.org/10.3390/cardiovascmed28010006

APA Style

Cook, S. T., & Cook, M. (2025). A Didactic Case of Long QT Associated with Pheochromocytoma. Cardiovascular Medicine, 28(1), 6. https://doi.org/10.3390/cardiovascmed28010006

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