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Cardiovascular Medicine is published by MDPI from Volume 28 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Editores Medicorum Helveticorum (EMH).

Cardiovasc. Med., Volume 21, Issue 4 (04 2018) – 4 articles

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7 pages, 848 KB  
Review
Acute Management of Bradycardia in the Emergency Setting
by Haran Burri and Nicolas Dayal
Cardiovasc. Med. 2018, 21(4), 98; https://doi.org/10.4414/cvm.2018.00554 - 18 Apr 2018
Cited by 2 | Viewed by 9
Abstract
Patients admitted with bradycardia may present with a variety of clinical pictures, ranging from fatigue to syncope and cardiac arrest [...] Full article
7 pages, 1174 KB  
Review
Wide-Complex Tachycardia
by Dagmar I. Keller
Cardiovasc. Med. 2018, 21(4), 90; https://doi.org/10.4414/cvm.2018.00555 - 18 Apr 2018
Viewed by 8
Abstract
Cardiac arrhythmia is a common cause for patient presentation in the emergency department [...] Full article
5 pages, 158 KB  
Review
Hypercholestérolémie Familiale: Quand y Penser et Quand Traiter?
by Nathalie Brun
Cardiovasc. Med. 2018, 21(4), 85; https://doi.org/10.4414/cvm.2018.00557 - 18 Apr 2018
Viewed by 11
Abstract
Familial hypercholesterolaemia: increasing physicians’ awareness in order to prevent early death. Familial hypercholesterolaemia (FH) is one of the most frequent autosomal dominant genetic conditions (1/200–300) and is still underdiagnosed and undertreated. Decreased clearance of circulating low-density lipoproteins (LDL) is the hallmark of this [...] Read more.
Familial hypercholesterolaemia: increasing physicians’ awareness in order to prevent early death. Familial hypercholesterolaemia (FH) is one of the most frequent autosomal dominant genetic conditions (1/200–300) and is still underdiagnosed and undertreated. Decreased clearance of circulating low-density lipoproteins (LDL) is the hallmark of this disease and is mostly secondary to mutations in the genes coding for the LDL receptor (LDLR), its ligand (APOB) or a regulatory protein (PCSK9). As a result of cumulative exposure to elevated LDL cholesterol levels from birth, FH patients experience major cardiovascular events approximately 13 years earlier than the general population, with a worse outcome. To proactively reduce the high cardiovascular burden of this disease, early identification of patients and initiation of tailored drug therapy is mandatory. A family history of premature cardiovascular disease (<55 years in men, <60 years in women) or severe hyperlipidaemia in first degree relatives is suggestive of FH and should prompt the physician to measure lipid levels, even in children. This review focuses on clinical diagnostic tools (Dutch Lipid Clinic Network score), cardiovascular risk stratification of patients and up-to-date therapeutic guidelines in order to help the physician in the management of these very high cardiovascular risk patients. Full article
6 pages, 478 KB  
Case Report
Coronary Sinus Reducer Device for Patients with Refractory Angina
by Peter C. Kahr, Andreas A. Giannopoulos, Ronny R. Buechel, Oliver Gaemperli, Shmuel Banai, Slayman Obeid and Thomas F. Lüscher
Cardiovasc. Med. 2018, 21(4), 105; https://doi.org/10.4414/cvm.2018.00553 - 18 Apr 2018
Cited by 1 | Viewed by 10
Abstract
Although fascinating improvements in surgical, interventional and medical treatment of patients with coronary artery disease have been achieved, a growing number of patients present with refractory angina despite optimal treatment. Currently, different approaches are being investigated to reduce angina and to improve quality [...] Read more.
Although fascinating improvements in surgical, interventional and medical treatment of patients with coronary artery disease have been achieved, a growing number of patients present with refractory angina despite optimal treatment. Currently, different approaches are being investigated to reduce angina and to improve quality of life in these patients with “no options”. Slowing of coronary venous drainage by implantation of a stent device that reduces the diameter of the coronary sinus is a promising approach, as demonstrated by a recent phase II trial. In this report we document the first implantation of this novel device at our institution in Switzerland, give a stepwise description of the implantation procedure and discuss the currently available literature with regard to the physiology and clinical indications for the so-called (coronary sinus) Reducer™ device. Full article
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