Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung
Abstract
:1. Introduction
2. Methods
2.1. Geometrical Development
2.2. Grid Generation and Model Validation
2.3. Numerical Methods
3. Results
3.1. Velocity Contours
3.2. Pressure Contours
3.3. Particle Deposition Efficiency
4. Discussion
5. Conclusions
Limitations of the Study
- This study focused on airflow and particle transport in human lungs for an inhalation scenario;
- The model used only a small number of lung generations, where the end of generation 5 was set to be the outlet;
- The airway size for elderly patient-specific lung can increase, and this study did not consider this effect;
- The upper lobe was not considered for the airway model to make the similar geometry for all cases and minimise the reconstruction complexity;
- This study did not consider any dynamic wall motion or airway deformation;
- Open outlet conditions and constant pressure were used at the outlets.
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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Properties | Air | Aerosol |
---|---|---|
Density (kg/m3) | 1.225 | 1100 |
Viscosity (kg/m-s) | 1.7893 × 105 | - |
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Islam, M.S.; Larpruenrudee, P.; Hossain, S.I.; Rahimi-Gorji, M.; Gu, Y.; Saha, S.C.; Paul, G. Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung. Int. J. Environ. Res. Public Health 2021, 18, 6239. https://doi.org/10.3390/ijerph18126239
Islam MS, Larpruenrudee P, Hossain SI, Rahimi-Gorji M, Gu Y, Saha SC, Paul G. Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung. International Journal of Environmental Research and Public Health. 2021; 18(12):6239. https://doi.org/10.3390/ijerph18126239
Chicago/Turabian StyleIslam, Mohammad S., Puchanee Larpruenrudee, Sheikh I. Hossain, Mohammad Rahimi-Gorji, Yuantong Gu, Suvash C. Saha, and Gunther Paul. 2021. "Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung" International Journal of Environmental Research and Public Health 18, no. 12: 6239. https://doi.org/10.3390/ijerph18126239