Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer

Marques, Vitor A.; Ferreira-Junior, João B.; Lemos, Thiago V.; Moraes, Rafael F.; Junior, José Roberto de S.; Alves, Rafael R.; Silva, Maria S.; Freitas-Junior, Ruffo de; Vieira, Carlos A.

doi:10.3390/ijerph17197289

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Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer

Vitor A. Marques

^1,*,

João B. Ferreira-Junior

Thiago V. Lemos

³,

Rafael F. Moraes

^1,4,

José Roberto de S. Junior

⁵,

Rafael R. Alves

Maria S. Silva

¹,

Ruffo de Freitas-Junior

⁶

and

Carlos A. Vieira

^1,7

Postgraduate Program in Health Sciences, Federal University of Goias, Goiania 74605-050, GO, Brazil

Federal Institute of Sudeste of Minas Gerais- Campus Rio Pomba, Rio Pomba 36180-000, MG, Brazil

School of Physical Education and Physiotherapy, State University of Goias, Goiania 74643-010, GO, Brazil

⁴

Teacher and Humanities Training School, Pontifical Catholic University of Goias, Goiania 74605-010, GO, Brazil

⁵

Postgraduation Program in Sciences and Technologies in Health, University of Brasília, Brasília 72220-275, DF, Brazil

⁶

Advanced Center for Diagnosis of Breast Cancer (CORA/HC/UFG/EBSERH), Clinical Hospital, Federal University of Goias, Goiania 74605-050, GO, Brazil

⁷

School of Physical Education and Dance, Federal University of Goias, Goiania 74690-900, GO, Brazil

Author to whom correspondence should be addressed.

Int. J. Environ. Res. Public Health 2020, 17(19), 7289; https://doi.org/10.3390/ijerph17197289

Received: 22 August 2020 / Revised: 1 October 2020 / Accepted: 3 October 2020 / Published: 6 October 2020

(This article belongs to the Special Issue Regulation of Muscle Mass, Exercise, Metabolism)

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Abstract

The study aimed to evaluate the effects of chemotherapy treatment on muscle strength, quality of life, fatigue, and anxiety in women with breast cancer. Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (control [CNT] group, 55.8 ± 8.4 years) answered questionnaires for evaluation of fatigue (Fatigue Scale), quality of life (Short-Form Healthy Survey [SF-36] questionnaire), and anxiety (State-Trait Anxiety Inventory [IDATE]) levels. Muscle strength was also assessed by an isometric grip test and an isokinetic knee extension test. Physical limitations, social and emotional domains of quality of life were lower in the BCT group in comparison to the CNT group (p = 0.002; p = 0.003; p = 0.0003, respectively). The other domains did not differ between groups (p > 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups (p > 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group (p = 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s⁻¹ (p = 0.95 and p = 0.61, respectively) and 180°.s⁻¹ (p = 0.94 and p = 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer. View Full-Text

Keywords: isokinetic test; isometric strength; physical exercise; physical activity; psychobiological profile

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MDPI and ACS Style

Marques, V.A.; Ferreira-Junior, J.B.; Lemos, T.V.; Moraes, R.F.; Junior, J.R.d.S.; Alves, R.R.; Silva, M.S.; Freitas-Junior, R.d.; Vieira, C.A. Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer. Int. J. Environ. Res. Public Health 2020, 17, 7289. https://doi.org/10.3390/ijerph17197289

AMA Style

Marques VA, Ferreira-Junior JB, Lemos TV, Moraes RF, Junior JRdS, Alves RR, Silva MS, Freitas-Junior Rd, Vieira CA. Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer. International Journal of Environmental Research and Public Health. 2020; 17(19):7289. https://doi.org/10.3390/ijerph17197289

Chicago/Turabian Style

Marques, Vitor A., João B. Ferreira-Junior, Thiago V. Lemos, Rafael F. Moraes, José R.d.S. Junior, Rafael R. Alves, Maria S. Silva, Ruffo d. Freitas-Junior, and Carlos A. Vieira. 2020. "Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer" International Journal of Environmental Research and Public Health 17, no. 19: 7289. https://doi.org/10.3390/ijerph17197289

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