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Open AccessConcept Paper

Application of the Safe-by-Design Concept in Crop Breeding Innovation

Wageningen Food Safety Research, Wageningen University and Research, Akkermaalsbos 2, P.O. Box 230, NL-6700 AE Wageningen, The Netherlands
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Int. J. Environ. Res. Public Health 2020, 17(17), 6420; https://doi.org/10.3390/ijerph17176420
Received: 22 July 2020 / Revised: 26 August 2020 / Accepted: 31 August 2020 / Published: 3 September 2020
The present paper proposes the application of the safe-by-design concept to crop breeding innovation with the aim to accommodate safety considerations for new agricultural food and feed products. Safe-by-design can be implemented in all stages of the innovation cycle of agricultural products, from the early stages of research and development towards the post-market stage. Our proposed application of safe-by-design can be part of “responsible research and innovation” concepts, because they share features such as risk prevention strategies and a participatory approach. Early awareness of potential safety issues can guide the development of agricultural products towards safe options, both at the process and product level, and thus may help to reduce extensive pre-market assessment studies that might otherwise be needed further downstream for regulatory product approval. Here, it is discussed how the proposed safe-by-design approach can be introduced into the development of safe food crops using emerging technologies, such as gene editing and synthetic biology, and how this may help to safeguard the safety of our food and feed supply in the light of the ongoing global innovations in agricultural crop breeding. View Full-Text
Keywords: crop breeding innovations; food; risk assessment; safe-by-design; synthetic biology crop breeding innovations; food; risk assessment; safe-by-design; synthetic biology
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van der Berg, J.P.; Kleter, G.A.; Battaglia, E.; Bouwman, L.M.S.; Kok, E.J. Application of the Safe-by-Design Concept in Crop Breeding Innovation. Int. J. Environ. Res. Public Health 2020, 17, 6420.

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