Next Article in Journal
Quantitative and Qualitative HPLC Analysis of Mycosporine-Like Amino Acids Extracted in Distilled Water for Cosmetical Uses in Four Rhodophyta
Previous Article in Journal
Functional Characterization of Carbohydrate-Binding Modules in a New Alginate Lyase, TsAly7B, from Thalassomonas sp. LD5
Previous Article in Special Issue
Increased Cell Detachment Ratio of Mesenchymal-Type Lung Cancer Cells on pH-Responsive Chitosan through the β3 Integrin
Open AccessArticle

Extraction of Hydroxyapatite Nanostructures from Marine Wastes for the Fabrication of Biopolymer-Based Porous Scaffolds

1
Department of Materials Science and Engineering, Sharif University of Technology, International Campus, P.O. Box 79417-76655, Kish Island, Iran
2
Department of Materials Science and Engineering, Sharif University of Technology, P.O. Box 11155-9161, Azadi Avenue, Tehran 14588, Iran
3
Department of Cell and Developmental Biology, School of Biological Sciences, College of Science, University of Tehran, P.O. Box 14155-6619, Tehran, Iran
4
Institute for Nanoscience and Nanotechnology, Sharif University of Technology, P.O. Box 11365-9466, Azadi Avenue, Tehran 14588, Iran
*
Author to whom correspondence should be addressed.
Both authors contributed equally to this work.
Mar. Drugs 2020, 18(1), 26; https://doi.org/10.3390/md18010026
Received: 29 November 2019 / Revised: 20 December 2019 / Accepted: 24 December 2019 / Published: 27 December 2019
(This article belongs to the Special Issue Marine Biomaterials 2020)
Three-dimensional porous nanocomposites consisting of gelatin-carboxymethylcellulose (CMC) cross-linked by carboxylic acids biopolymers and monophasic hydroxyapatite (HA) nanostructures were fabricated by lyophilization, for soft-bone-tissue engineering. The bioactive ceramic nanostructures were prepared by a novel wet-chemical and low-temperature procedure from marine wastes containing calcium carbonates. The effect of surface-active molecules, including sodium dodecyl sulfate (SDS) and hexadecyltrimethylammonium bromide (CTAB), on the morphology of HA nanostructures is shown. It is demonstrated that highly bioactive and monophasic HA nanorods with an aspect ratio > 10 can be synthesized in the presence of SDS. In vitro studies on the bioactive biopolymer composite scaffolds with varying pore sizes, from 100 to 300 μm, determine the capacity of the developed procedure to convert marine wastes to profitable composites for tissue engineering. View Full-Text
Keywords: marine waste; biopolymer; tissue engineering; cytotoxicity marine waste; biopolymer; tissue engineering; cytotoxicity
Show Figures

Figure 1

MDPI and ACS Style

Gheysari, H.; Mohandes, F.; Mazaheri, M.; Dolatyar, B.; Askari, M.; Simchi, A. Extraction of Hydroxyapatite Nanostructures from Marine Wastes for the Fabrication of Biopolymer-Based Porous Scaffolds. Mar. Drugs 2020, 18, 26.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop