Next Article in Journal
Haloarchaeal Carotenoids: Healthy Novel Compounds from Extreme Environments
Previous Article in Journal
Penicamide A, A Unique N,N′-Ketal Quinazolinone Alkaloid from Ascidian-Derived Fungus Penicillium sp. 4829
Previous Article in Special Issue
Structural and Serological Studies of the O6-Related Antigen of Aeromonas veronii bv. sobria Strain K557 Isolated from Cyprinus carpio on a Polish Fish Farm, which Contains l-perosamine (4-amino-4,6-dideoxy-l-mannose), a Unique Sugar Characteristic for Aeromonas Serogroup O6
Open AccessFeature PaperArticle

The Distribution of Asterosaponins, Polyhydroxysteroids and Related Glycosides in Different Body Components of the Far Eastern Starfish Lethasterias fusca

G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of Russian Academy of Sciences, 159 Prospect 100-letiya Vladivostoku, Vladivostok 690022, Russia
*
Author to whom correspondence should be addressed.
Mar. Drugs 2019, 17(9), 523; https://doi.org/10.3390/md17090523
Received: 15 August 2019 / Revised: 30 August 2019 / Accepted: 30 August 2019 / Published: 6 September 2019
(This article belongs to the Special Issue Marine Glycoconjugates: Trends and Perspectives)
Glycoconjugated and other polar steroids of starfish have unique chemical structures and show a broad spectrum of biological activities. However, their biological functions remain not well established. Possible biological roles of these metabolites might be indicated by the studies on their distribution in the organism–producer. In order to investigate the localization of polar steroids in body components of the Far Eastern starfish Lethasterias fusca, chemical constituents of body walls, gonads, stomach, pyloric caeca, and coelomic fluid were studied by nanoflow liquid chromatography/mass spectrometry with captive spray ionization (nLC/CSI–QTOF–MS). It has been shown that the levels of polar steroids in the studied body components are qualitatively and quantitatively different. Generally, the obtained data confirmed earlier made assumptions about the digestive function of polyhydroxysteroids and protective role of asterosaponins. The highest level of polar steroids was found in the stomach. Asterosaponins were found in all body components, the main portion of free polyhydroxysteroids and related glycosides were located in the pyloric caeca. In addition, a great inter-individual variability was found in the content of most polar steroids, which may be associated with the peculiarities in their individual physiologic status. View Full-Text
Keywords: starfish; Lethasterias fusca; asterosaponins; polyhydroxysteroids; glycosides; body components; distribution starfish; Lethasterias fusca; asterosaponins; polyhydroxysteroids; glycosides; body components; distribution
Show Figures

Figure 1

MDPI and ACS Style

Popov, R.S.; Ivanchina, N.V.; Kicha, A.A.; Malyarenko, T.V.; Grebnev, B.B.; Stonik, V.A.; Dmitrenok, P.S. The Distribution of Asterosaponins, Polyhydroxysteroids and Related Glycosides in Different Body Components of the Far Eastern Starfish Lethasterias fusca. Mar. Drugs 2019, 17, 523.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

1
Back to TopTop