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Open AccessArticle

Enhancing the Extraction of Polysaccharides and Antioxidants from Macroalgae Using Sequential Hydrothermal-Assisted Extraction Followed by Ultrasound and Thermal Technologies

1
School of Veterinary Medicine, Veterinary Science Centre, University College Dublin, Belfield, Dublin 4, Ireland
2
School of Agriculture and Food Science, University College Dublin, Lyons Research Farm, Celbridge, Co. Kildare W23 ENY2, Ireland
3
TEAGASC, Food Research Centre, Ashtown, Dublin D15 KN3K, Ireland
*
Author to whom correspondence should be addressed.
Mar. Drugs 2019, 17(8), 457; https://doi.org/10.3390/md17080457
Received: 20 June 2019 / Revised: 31 July 2019 / Accepted: 2 August 2019 / Published: 5 August 2019
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Abstract

Fucose sulphated polysaccharides (FSPs) and glucans have recently attracted the attention of the scientific community due to their wide range of biological activities. Both polysaccharides should ideally be selectively extracted using innovative technologies with high extraction efficiency. This study aims to: (1) Optimise the extraction variables used in hydrothermal-assisted extraction (HAE) to obtain high yields of FSPs, total glucans, and antioxidants from Laminaria hyperborea; (2) to apply these optimised protocols to other brown macroalgae; and (3) to explore the application of ultrasound and thermal technologies to increase the recovery of polysaccharides from the residual biomass. Box-Behnken design (three-factor, four-levels) was employed to optimise the HAE variables, and principal component analysis was used to evaluate the recovery of polysaccharides from the residual biomass. The optimal HAE conditions were 120 °C, 80.9 min, and 12.02 mL/g macroalgae from L. hyperborea. The best sequential application of ultrasound and thermal treatment achieved an additional 2971.7 ± 61.9 mg fucose/100 g dried macroalgal residue (dmr) from Ascophyllum nodosum and 908.0 ± 51.4 mg total glucans/100 g dmr from L. hyperborea macroalgal residues. View Full-Text
Keywords: fucoidan; glucan; laminarin; carbohydrate; innovative technology; biorefinery; functional food; optimisation; response surface methodology fucoidan; glucan; laminarin; carbohydrate; innovative technology; biorefinery; functional food; optimisation; response surface methodology
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Garcia-Vaquero, M.; O’Doherty, J.V.; Tiwari, B.K.; Sweeney, T.; Rajauria, G. Enhancing the Extraction of Polysaccharides and Antioxidants from Macroalgae Using Sequential Hydrothermal-Assisted Extraction Followed by Ultrasound and Thermal Technologies. Mar. Drugs 2019, 17, 457.

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