Next Article in Journal
Stereo-Selective Pharmacokinetics of Ilimaquinone Epimers Extracted from a Marine Sponge in Rats
Next Article in Special Issue
Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms
Previous Article in Journal
Preparation and Evaluation of Peptides with Potential Antioxidant Activity by Microwave Assisted Enzymatic Hydrolysis of Collagen from Sea Cucumber Acaudina Molpadioides Obtained from Zhejiang Province in China
Previous Article in Special Issue
In Vitro Immunostimulating Activity of Sulfated Polysaccharides from Caulerpa cupressoides Var. Flabellata
Open AccessReview

Antithrombotics from the Sea: Polysaccharides and Beyond

1
LQOF—Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
2
CIIMAR—Centro Interdisciplinar de Investigação Marinha e Ambiental, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos S/N, 4450-208 Matosinhos, Portugal
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Mar. Drugs 2019, 17(3), 170; https://doi.org/10.3390/md17030170
Received: 31 January 2019 / Revised: 1 March 2019 / Accepted: 13 March 2019 / Published: 16 March 2019
(This article belongs to the Special Issue Marine Polysaccharides in Pharmaceutical Applications)
Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural products with antithrombotic activity has increased in the last few years, and reports show a wide diversity in scaffolds, beyond the polysaccharide framework. While there are several reviews highlighting the anticoagulant and antithrombotic activities of marine-derived sulfated polysaccharides, reports including other molecules are sparse. Therefore, the present paper provides an update of the recent progress in marine-derived sulfated polysaccharides and quotes other scaffolds that are being considered for investigation due to their antithrombotic effect. View Full-Text
Keywords: marine-derived; polysaccharide; anticoagulant; antithrombotic; antiplatelet; glycosaminoglycans; sulfated fucans; sulfated galactans marine-derived; polysaccharide; anticoagulant; antithrombotic; antiplatelet; glycosaminoglycans; sulfated fucans; sulfated galactans
Show Figures

Graphical abstract

MDPI and ACS Style

Carvalhal, F.; Cristelo, R.R.; Resende, D.I.S.P.; Pinto, M.M.M.; Sousa, E.; Correia-da-Silva, M. Antithrombotics from the Sea: Polysaccharides and Beyond. Mar. Drugs 2019, 17, 170. https://doi.org/10.3390/md17030170

AMA Style

Carvalhal F, Cristelo RR, Resende DISP, Pinto MMM, Sousa E, Correia-da-Silva M. Antithrombotics from the Sea: Polysaccharides and Beyond. Marine Drugs. 2019; 17(3):170. https://doi.org/10.3390/md17030170

Chicago/Turabian Style

Carvalhal, Francisca; Cristelo, Ricardo R.; Resende, Diana I.S.P.; Pinto, Madalena M.M.; Sousa, Emília; Correia-da-Silva, Marta. 2019. "Antithrombotics from the Sea: Polysaccharides and Beyond" Mar. Drugs 17, no. 3: 170. https://doi.org/10.3390/md17030170

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop