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Computational Methodologies in the Exploration of Marine Natural Product Leads
Open AccessReview

Potential Role of Seaweed Polyphenols in Cardiovascular-Associated Disorders

1
Department of Pharmacology, School of Pharmacy, University of Granada, 18071 Granada, Spain
2
Instituto de Investigación Biosanitaria de Granada (Ibs.GRANADA), 18071 Granada, Spain
3
CIBER-EHD, Department of Pharmacology, Centre for Biomedical Research (CIBM), University of Granada, 18071 Granada, Spain
*
Author to whom correspondence should be addressed.
Mar. Drugs 2018, 16(8), 250; https://doi.org/10.3390/md16080250
Received: 29 June 2018 / Revised: 22 July 2018 / Accepted: 26 July 2018 / Published: 28 July 2018
(This article belongs to the Special Issue Progress on Marine Natural Products as Lead Compounds)
The beneficial effects of various polyphenols with plant origins on different cardiovascular-associated disorders, such as hypertension, diabetes mellitus type 2 and metabolic syndrome are well known. Recently, marine crude-drugs are emerging as potential treatments in many noncommunicable conditions, including those involving the cardiovascular system. Among the active compounds responsible for these activities, seaweed polyphenols seem to play a key role. The aim of the present review is to summarise the current knowledge about the beneficial effects reported for edible seaweed polyphenols in the amelioration of these prevalent conditions, focusing on both preclinical and clinical studies. This review will help to establish the basis for future studies in this promising field. View Full-Text
Keywords: cardiovascular diseases; hypertension; immune response; metabolic syndrome; seaweed polyphenols cardiovascular diseases; hypertension; immune response; metabolic syndrome; seaweed polyphenols
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Gómez-Guzmán, M.; Rodríguez-Nogales, A.; Algieri, F.; Gálvez, J. Potential Role of Seaweed Polyphenols in Cardiovascular-Associated Disorders. Mar. Drugs 2018, 16, 250.

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