Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
1
Department of Anatomy and Neuroscience, University College Cork, T12XF62 Cork, Ireland
2
APC Microbiome Ireland, Teagasc Food Research Centre, Moorepark, Fermoy, P61 C996 Cork, Ireland
3
School of Microbiology, University College Cork, T12YT20 Cork, Ireland
4
Marigot Ltd., Strand Farm, Currabinny, Carrigaline, P43NN62 Cork, Ireland
5
APC Microbiome Ireland, University College Cork, T12YT20 Cork, Ireland
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Mar. Drugs 2018, 16(6), 216; https://doi.org/10.3390/md16060216
Received: 18 March 2018 / Revised: 25 April 2018 / Accepted: 9 June 2018 / Published: 20 June 2018
(This article belongs to the Special Issue Marine Health Compounds: From Extraction to Food and Pharmaceutical Application)
Abstract
Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar “Western diet” have been associated with health problems such as obesity, inflammatory bowel diseases, and cardiovascular diseases, as well as metabolic, immune, and psychiatric disorders. It is now recognized that modulating the diversity of gut microbiota, the population of intestinal bacteria, through dietary intervention can significantly impact upon gut health as well as systemic and brain health. In the current study, we show that supplementation with a seaweed and seawater-derived functional food ingredient rich in bioactive calcium and magnesium (0.1% supplementation) as well as 70 other trace elements, significantly enhanced the gut microbial diversity in adult male rats. Given the significant impact of gut microbiota on health, these results position this marine multi-mineral blend (MMB) as a promising digestive-health promoting functional food ingredient. View Full-TextKeywords:
marine extract; calcium; magnesium; gut microbial diversity; rat
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Crowley, E.K.; Long-Smith, C.M.; Murphy, A.; Patterson, E.; Murphy, K.; O’Gorman, D.M.; Stanton, C.; Nolan, Y.M. Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota. Mar. Drugs 2018, 16, 216.
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