Next Article in Journal
Characterization of Properties and Transglycosylation Abilities of Recombinant α-Galactosidase from Cold-Adapted Marine Bacterium Pseudoalteromonas KMM 701 and Its C494N and D451A Mutants
Previous Article in Journal
Marine Peroxy Sesquiterpenoids Induce Apoptosis by Modulation of Nrf2-ARE Signaling in HCT116 Colon Cancer Cells
Article Menu

Export Article

Open AccessReview
Mar. Drugs 2018, 16(10), 348; https://doi.org/10.3390/md16100348

Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae

1
Faculty of Food Technology Osijek, Josip Juraj Strossmayer University of Osijek, FranjeKuhača 20, 31000 Osijek, Croatia
2
Faculty of Chemistry and Technology, University of Split, R. Boškovića 35, 21000 Split, Croatia
*
Author to whom correspondence should be addressed.
Received: 27 August 2018 / Revised: 16 September 2018 / Accepted: 20 September 2018 / Published: 23 September 2018
Full-Text   |   PDF [2129 KB, uploaded 23 September 2018]   |  

Abstract

Marine macroalgae represent a rich source of bioactive compounds that can be implemented in various food, cosmetic, and pharmaceutical products for health improvement. It has been proven that these bioactive compounds, such as polyphenols, polysaccharides, carotenoids, and ω-3 fatty acids possess bioactivity. For the extraction of these compounds, modern methods (Supercritical Fluid Extraction (SFE), Subcritical Water Extraction (SWE), Ultrasound-Assisted Extraction (UAE), and Microwave-Assisted Extraction (MAE)) have been used due to their advantages over the conventional methods. The process parameters of each method must be optimized for obtaining the extracts with the targeted bioactive compounds. In distinction from the existing reviews, the present review provides novelty with respect to: (a) presenting systematically the selected process parameters of SFE (temperature, time, pressure, use of co-solvents), SWE (temperature, time, pressure, solid-solvent ratio), UAE (temperature, time, frequency, power, solid-solvent ratio), and MAE (temperature, time, frequency, power, solvent type) applied for the extractions of marine macroalgae; (b) reporting the major groups or individual compounds extracted with their biological activities (if determined); and, (c) updating available references. View Full-Text
Keywords: marine macroalgae; supercritical CO2 extraction; subcritical water extraction; ultrasound-assisted extraction; microwave-assisted extraction; bioactive compounds; biological activity marine macroalgae; supercritical CO2 extraction; subcritical water extraction; ultrasound-assisted extraction; microwave-assisted extraction; bioactive compounds; biological activity
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Cikoš, A.-M.; Jokić, S.; Šubarić, D.; Jerković, I. Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae. Mar. Drugs 2018, 16, 348.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top