The Importance of Out-of-Office Blood Pressure Measurement, as Highlighted by the Correlation with Left Ventricular Hypertrophy in an Untreated Hypertensive Population
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Blood Pressure Measurements
2.3. Blood Pressure Phenotypes
2.4. Echocardiogram
2.5. Statistical Analysis
3. Results
3.1. Descriptive Statistics
3.2. Univariate Logistic Regression Analysis of Left Ventricular Hypertrophy using Different Blood Pressure Measurements
3.3. Pearson Correlation between Left Ventricular Mass Index and Different Blood Pressure Parameters
3.4. Prevalence of Different Blood Pressure Phenotypes in Patients with Left Ventricular Hypertrophy
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | Mean ± SD |
---|---|
Age (years) | 58.0 ± 15 |
Sex (male %) | 40.8 |
BMI (kg/m2) | 29.8 ± 5.7 |
eGFR (ml/min/1.73 m2) | 85.6 ± 21.7 |
Dyslipidemia (%) | 44 |
Diabetes mellitus (%) | 16.9 |
Current smokers (%) | 21.8 |
Alcohol (yes%) | 19.7 |
Mean 24 h SBP (mmHg) | 129.9 ± 15.7 |
Mean 24 h DBP (mmHg) | 77.2 ± 11.7 |
Mean home SBP (mmHg) | 140 ± 14.8 |
Mean home DBP (mmHg) | 83.1 ± 11.3 |
Mean office SBP (mmHg) | 145.6 ± 17.9 |
Mean office DBP (mmHg) | 85.2 ± 12.3 |
LV hypertrophy (%) | 36.8 |
Variable | OR | 95% Cl | p |
---|---|---|---|
Based on 24 h ABPM | |||
Mean 24 h SBP | 1.93 | 1.29–2.91 | <0.05 |
Mean 24 h DBP | 1.30 | 1.16–1.80 | <0.05 |
Daytime SBP | 1.11 | 1.01–1.82 | <0.05 |
Daytime DBP | 1.13 | 1.09–1.17 | <0.05 |
Nighttime SBP | 2.11 | 1.04–4.31 | <0.05 |
Nighttime DBP | 0.45 | 0.19–1.07 | >0.05 |
Based on HBPM | |||
Mean SBP | 1.05 | 1.01–1.12 | <0.05 |
Mean DBP | 1.23 | 0.38–3.93 | >0.05 |
Daytime SBP | 0.93 | 0.57–1.49 | >0.05 |
Daytime DBP | 1.32 | 0.67–2.59 | >0.05 |
Nighttime SBP | 1.07 | 0.72–1.57 | >0.05 |
Nighttime DBP | 0.81 | 0.45–1.44 | >0.05 |
Based on OBPM | |||
Mean office SBP | 1.03 | 0.99–1.08 | >0.05 |
Mean office DBP | 1.02 | 0.94–1.09 | >0.05 |
Variable | r | p |
---|---|---|
Based on 24 h ABPM | ||
Mean 24 h SBP | 0.58 | <0.05 |
Mean 24 h DBP | −0.07 | >0.05 |
Daytime SBP | 0.59 | <0.05 |
Daytime DPB | −0.1 | >0.05 |
Nighttime SBP | 0.57 | <0.05 |
Nighttime DBP | 0.01 | >0.05 |
Based on HBPM | ||
Mean SBP | 0.29 | <0.05 |
Mean DBP | 0.07 | >0.05 |
Daytime SBP | 0.28 | >0.05 |
Daytime DBP | 0.07 | >0.05 |
Nighttime SBP | 0.22 | <0.05 |
Nighttime DBP | 0.06 | >0.05 |
Based on OBPM | ||
Mean office SBP | 0.07 | >0.05 |
Mean office DBP | −0.04 | >0.05 |
Different BP Phenotypes | ||||
---|---|---|---|---|
Within Population Presenting LV Hypertrophy | Based on 24 h ABPM | |||
Normotension | White-Coat | Masked | Hypertension | |
7.9% | 11.5% | 32.7% | 48.1% | |
Based on HBPM | ||||
Normotension | White-Coat | Masked | Hypertension | |
17.9% | 18.4% | 23.7% | 40% | |
Dipping status during night | ||||
Extreme Dipping | Dipping | Non-Dipping | Reverse | |
7.3% | 13% | 59.3% | 20.4% |
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Antza, C.; Tziomalos, G.; Kostopoulos, G.; Trakatelli, C.; Kotsis, V. The Importance of Out-of-Office Blood Pressure Measurement, as Highlighted by the Correlation with Left Ventricular Hypertrophy in an Untreated Hypertensive Population. Medicina 2023, 59, 1636. https://doi.org/10.3390/medicina59091636
Antza C, Tziomalos G, Kostopoulos G, Trakatelli C, Kotsis V. The Importance of Out-of-Office Blood Pressure Measurement, as Highlighted by the Correlation with Left Ventricular Hypertrophy in an Untreated Hypertensive Population. Medicina. 2023; 59(9):1636. https://doi.org/10.3390/medicina59091636
Chicago/Turabian StyleAntza, Christina, Georgios Tziomalos, Georgios Kostopoulos, Christina Trakatelli, and Vasilios Kotsis. 2023. "The Importance of Out-of-Office Blood Pressure Measurement, as Highlighted by the Correlation with Left Ventricular Hypertrophy in an Untreated Hypertensive Population" Medicina 59, no. 9: 1636. https://doi.org/10.3390/medicina59091636