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Volume 58
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Article

The Ten-Year Risk Prediction for Cardiovascular Disease for Malaysian Adults Using the Laboratory-Based and Office-Based (Globorisk) Prediction Model

by
Che Muhammad Nur Hidayat Che Nawi
1,
Mohd Azahadi Omar
2,
Thomas Keegan
3,
Yong-Poh Yu
4 and
Kamarul Imran Musa
1,*
1
Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia
2
Sector for Biostatistics & Data Repository, National Institutes of Health, Ministry of Health, Shah Alam 40170, Selangor, Malaysia
3
Faculty of Health and Medicine, Lancaster Medical School, Lancaster University, Lancaster LA1 4YW, UK
4
Redbeat Academy, AirAsia Berhad, Kuala Lumpur 50470, Selangor, Malaysia
*
Author to whom correspondence should be addressed.
Medicina 2022, 58(5), 656; https://doi.org/10.3390/medicina58050656
Submission received: 17 April 2022 / Revised: 30 April 2022 / Accepted: 4 May 2022 / Published: 12 May 2022
(This article belongs to the Section Epidemiology & Public Health)
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Abstract

Background and Objectives: Globorisk is a well-validated risk prediction model that predicts cardiovascular disease (CVD) in the national population of all countries. We aim to apply the Globorisk calculator and provide the overall, sex-specific, ethnic-specific, region-specific, and state-specific 10-year risk for CVD among Malaysian adults. Materials and Methods: Using Malaysia’s risk factor levels and CVD event rates, we calculated the laboratory-based and office-based risk scores to predict the 10-year risk for fatal CVD and fatal plus non-fatal CVD for the Malaysian adult population. We analysed data from 8253 participants from the 2015 nationwide Malaysian National Health and Morbidity Survey (NHMS 2015). The average risk for the 10-year fatal and fatal plus non-fatal CVD was calculated, and participants were further grouped into four categories: low risk (<10% risk for CVD), high risk A (≥10%), high risk B (≥20%), and high risk C (≥30%). Results: Results were reported for all participants and were then stratified by sex, ethnicity, region, and state. The average risks for laboratory-based fatal CVD, laboratory-based fatal plus non-fatal CVD, and office-based fatal plus non-fatal CVD were 0.07 (SD = 0.10), 0.14 (SD = 0.12), and 0.11 (SD = 0.09), respectively. Conclusions: There were substantial differences in terms of the sex-, ethnicity- and state-specific Globorisk risk scores obtained.
Keywords: cardiovascular disease; ten-year risk prediction; Globorisk; Malaysia cardiovascular disease; ten-year risk prediction; Globorisk; Malaysia

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MDPI and ACS Style

Che Nawi, C.M.N.H.; Omar, M.A.; Keegan, T.; Yu, Y.-P.; Musa, K.I. The Ten-Year Risk Prediction for Cardiovascular Disease for Malaysian Adults Using the Laboratory-Based and Office-Based (Globorisk) Prediction Model. Medicina 2022, 58, 656. https://doi.org/10.3390/medicina58050656

AMA Style

Che Nawi CMNH, Omar MA, Keegan T, Yu Y-P, Musa KI. The Ten-Year Risk Prediction for Cardiovascular Disease for Malaysian Adults Using the Laboratory-Based and Office-Based (Globorisk) Prediction Model. Medicina. 2022; 58(5):656. https://doi.org/10.3390/medicina58050656

Chicago/Turabian Style

Che Nawi, Che Muhammad Nur Hidayat, Mohd Azahadi Omar, Thomas Keegan, Yong-Poh Yu, and Kamarul Imran Musa. 2022. "The Ten-Year Risk Prediction for Cardiovascular Disease for Malaysian Adults Using the Laboratory-Based and Office-Based (Globorisk) Prediction Model" Medicina 58, no. 5: 656. https://doi.org/10.3390/medicina58050656

APA Style

Che Nawi, C. M. N. H., Omar, M. A., Keegan, T., Yu, Y.-P., & Musa, K. I. (2022). The Ten-Year Risk Prediction for Cardiovascular Disease for Malaysian Adults Using the Laboratory-Based and Office-Based (Globorisk) Prediction Model. Medicina, 58(5), 656. https://doi.org/10.3390/medicina58050656

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