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Volume 58
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Article

Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study

by
Sukriti Das
1,
Nicola Montemurro
2,*,
Musannah Ashfaq
3,
Dipankar Ghosh
3,
Asit Chandra Sarker
3,
Akhlaque Hossain Khan
1,
Sharbari Dey
1 and
Bipin Chaurasia
3
1
Department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Dhaka 1205, Bangladesh
2
Department of Neurosurgery, Azienda Ospedaliera Universitaria Pisana (AOUP), University of Pisa, 56100 Pisa, Italy
3
Department of Neurosurgery, Bangladesh Medical College and University, Dhaka 1205, Bangladesh
*
Author to whom correspondence should be addressed.
Medicina 2022, 58(2), 281; https://doi.org/10.3390/medicina58020281
Submission received: 7 January 2022 / Revised: 7 February 2022 / Accepted: 11 February 2022 / Published: 13 February 2022
(This article belongs to the Section Surgery)
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Abstract

Background and Objectives: Ventriculoperitoneal Shunt (VPS) and Endoscopic Third Ventriculostomy (ETV) are both gold standard procedures to reduce intracranial pressure (ICP) in patients with obstructive hydrocephalus, which often results in papilledema. This comparative study was carried out at the Department of Neurosurgery of Dhaka Medical College and Hospital to compare the efficacy of VPS and ETV in the resolution of papilledema in 18 patients with obstructive hydrocephalus. Materials and Methods: The success of CSF diversion was evaluated by a decrease in retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT) and modified Frisen grading of papilledema at the same time. The statistical analyses were carried out by using paired sample t test and the Spearman’s correlation coefficient test. The level of significance (p value) was set at <0.05. Results: After 7 days, both VPS and ETV were able to reduce RNFL thickness of both eyes with a p value = 0.016 (right eye) and 0.003 (left eye) in group A (VPS) and with a p value <0.001 (both eyes) in group B (ETV). Change of Frisen grading after CSF diversion was not satisfying for both the procedures with p value > 0.05. Further, the inter-group comparison between VPS and ETV showed no difference in decreasing RNFL thickness and modified Frisen grading (p value = 0.56). Conclusion: VPS and ETV procedures both appear very efficient in treating obstructive hydrocephalus, which in turn reduces papilledema in these patients. This paper is preliminary and requires further work.
Keywords: endoscopic third ventriculostomy; ETV; neurosurgery; obstructive hydrocephalus; papilledema; ventriculoperitoneal shunt; VPS endoscopic third ventriculostomy; ETV; neurosurgery; obstructive hydrocephalus; papilledema; ventriculoperitoneal shunt; VPS

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MDPI and ACS Style

Das, S.; Montemurro, N.; Ashfaq, M.; Ghosh, D.; Sarker, A.C.; Khan, A.H.; Dey, S.; Chaurasia, B. Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study. Medicina 2022, 58, 281. https://doi.org/10.3390/medicina58020281

AMA Style

Das S, Montemurro N, Ashfaq M, Ghosh D, Sarker AC, Khan AH, Dey S, Chaurasia B. Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study. Medicina. 2022; 58(2):281. https://doi.org/10.3390/medicina58020281

Chicago/Turabian Style

Das, Sukriti, Nicola Montemurro, Musannah Ashfaq, Dipankar Ghosh, Asit Chandra Sarker, Akhlaque Hossain Khan, Sharbari Dey, and Bipin Chaurasia. 2022. "Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study" Medicina 58, no. 2: 281. https://doi.org/10.3390/medicina58020281

APA Style

Das, S., Montemurro, N., Ashfaq, M., Ghosh, D., Sarker, A. C., Khan, A. H., Dey, S., & Chaurasia, B. (2022). Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study. Medicina, 58(2), 281. https://doi.org/10.3390/medicina58020281

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