Post-Diverticulitis Colonoscopy Was Not Associated with Higher Colonic Adenoma and Carcinoma: A Multicenter Case–Control Study
Abstract
:1. Introduction
2. Materials and Methods
3. Study Endpoints
4. Statistical Analysis
5. Results
5.1. Demographics, Baseline Characteristics, and Colonoscopic Findings
5.2. Univariate Analysis of the Association between Colonoscopic Findings and Diverticulitis
5.3. Parameters Associated with the Diagnosis of Colonic Adenomas and CRC among Patients Who Had Diverticulitis
5.4. Association of Diverticulitis Severity with Colonoscopic Diagnosis of Colonic Adenoma and CRC
6. Discussion
7. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameter | Group A (with Diverticulitis) | Group B (Diverticulosis) | p-Value |
---|---|---|---|
Number of patients | 134 | 233 | - |
Age | 68.3 ± 10.5 | 70.5 ± 7.8 | 0.01 |
Gender, N (%) | |||
Male | 93 (69.4) | 149 (63.9) | 0.28 |
Female | 41 (30.6) | 84 (36.1) | |
Medical history | |||
Hyperlipidemia | 80 (59.7) | 136 (58.4) | 0.80 |
Hypertension | 97 (72.4) | 161 (69.5) | 0.51 |
Chornic renal failure | 5 (3.7) | 16 (6.9) | 0.21 |
Congestive heart failure | 5 (3.7) | 15 (6.4) | 0.27 |
Diabetes mellitus | 106 (79.1) | 45 (19.3) | <0.0001 |
Obesity | 106 (79.1) | 43 (18.5) | <0.0001 |
Smoking, N (%) | 43 (31.8) | 50 (21.5) | 0.02 |
Statin use, N (%) | 62 (46.3) | 97 (41.6) | 0.38 |
NSAID use, N (%) | 13 (9.7) | 19 (8.2) | 0.61 |
Aspirin use, N (%) | 81 (60) | 127 (54.5) | 0.27 |
Colonoscopic findings, N (%) | |||
Adenomas and CRC | 44 (32.8) | 57 (24.5) | 0.08 |
CRC alone | 2 (1.5) | 4 (1.7) | 0.87 |
Adenomas alone | 42 (31.3) | 53 (22.7) | 0.07 |
Adenoma detection rate, N (%) | 42 (31.3) | 53 (22.7) | - |
Pathological Findings | Odds Ratio | 95% CI | p-Value |
---|---|---|---|
Adenomas and CRC | 1.51 | 0.94–2.41 | 0.085 |
Adenomas alone | 1.60 | 0.96–2.50 | 0.07 |
CRC alone | 0.87 | 0.16–4.80 | 0.87 |
Parameter | Group C | Group D | p-Value |
---|---|---|---|
Number of patients | 44 | 90 | |
Age | 69.02 ± 9.5 | 67.9 ± 10.9 | 0.27 |
Gender, N (%) | |||
Male | 38 (86.4) | 55 (61.1) | 0.001 for male |
Female | 6 (13.6) | 35 (38.9) | |
Medical history | |||
Hyperlipidemia | 24 (54.5) | 56 (62.2) | 0.19 |
Hypertension | 31 (70.5) | 66 (73.3) | 0.36 |
Chornic renal failure | 2 (4.5) | 3 (3.3) | 0.36 |
Congestive heart failure | 3 (6.8) | 2 (2.2) | 0.09 |
Diabetes mellitus | 34 (77.3) | 72 (80) | 0.35 |
Obesity | 34 (77.3) | 72 (80) | 0.35 |
Smoking, N (%) | 40 (90.5) | 3 (3.4) | <0.0001 |
Statin use, N (%) | 21 (47.7) | 41 (45.6) | 0.40 |
NSAID use, N (%) | 6 (13.6) | 7 (7.8) | 0.14 |
Aspirin use, N (%) | 28 (63.6) | 53 (58.9) | 0.30 |
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Mari, A.; Khoury, T.; Sbeit, W. Post-Diverticulitis Colonoscopy Was Not Associated with Higher Colonic Adenoma and Carcinoma: A Multicenter Case–Control Study. Medicina 2021, 57, 682. https://doi.org/10.3390/medicina57070682
Mari A, Khoury T, Sbeit W. Post-Diverticulitis Colonoscopy Was Not Associated with Higher Colonic Adenoma and Carcinoma: A Multicenter Case–Control Study. Medicina. 2021; 57(7):682. https://doi.org/10.3390/medicina57070682
Chicago/Turabian StyleMari, Amir, Tawfik Khoury, and Wisam Sbeit. 2021. "Post-Diverticulitis Colonoscopy Was Not Associated with Higher Colonic Adenoma and Carcinoma: A Multicenter Case–Control Study" Medicina 57, no. 7: 682. https://doi.org/10.3390/medicina57070682