Next Article in Journal
Modern Technologies in the Rehabilitation of Patients with Multiple Sclerosis and Their Potential Application in Times of COVID-19
Next Article in Special Issue
Prevalence of Pathogens and Other Microorganisms in Premenopausal and Postmenopausal Women with Vulvovaginal Symptoms: A Retrospective Study in a Single Institute in South Korea
Previous Article in Journal
Bevacizumab-Containing Chemoimmunotherapy for Recurrent Non-Small-Cell Lung Cancer after Chemoradiotherapy: Case Report
Previous Article in Special Issue
Expectations and Challenges of First-Line Maintenance Therapy for Advanced Ovarian Cancer
 
 
Article

Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study

Department of Obstetrics and Gynecology, Iwate Medical University School of Medicine, Shiwa, Iwate 028-3695, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Masafumi Koshiyama
Medicina 2021, 57(6), 548; https://doi.org/10.3390/medicina57060548
Received: 19 April 2021 / Revised: 24 May 2021 / Accepted: 27 May 2021 / Published: 29 May 2021
(This article belongs to the Special Issue Diagnosis, Prevention and Treatment for Diseases Specific to Women)
Background and Objectives: In October 2018, the International Federation of Gynecology and Obstetrics (FIGO) revised its classification of advanced stages of cervical cancer. The main points of the classification are as follows: stage IIIC is newly established; pelvic lymph node metastasis is stage IIIC1; and para-aortic lymph node metastasis is stage IIIC2. Currently, in Japan, radical hysterectomy is performed in advanced stages IA2 to IIB of FIGO2014, and concurrent chemoradiotherapy (CCRT) is recommended for patients with positive lymph nodes. However, the efficacy of CCRT is not always satisfactory. The aim of this study was to compare postoperative adjuvant chemotherapy (CT) and postoperative CCRT in stage IIIC1 patients. Materials and Methods: Of the 40 patients who had undergone a radical hysterectomy at Iwate Medical University between January 2011 and December 2016 and were pathologically diagnosed as having positive pelvic lymph nodes, 21 patients in the adjuvant CT group and 19 patients in the postoperative CCRT group were compared. Results: The 5 year survival rates were 77.9% in the CT group and 74.7% in the CCRT group, with no significant difference. There was no significant difference in overall survival or progression-free survival between the two groups. There was no significant difference between CT and CCRT in postoperative adjuvant therapy in the new classification IIIC1 stage. Conclusions: The results of the prospective Japanese Gynecologic Oncology Group (JGOG) 1082 study are pending, but the present results suggest that CT may be a treatment option in rural areas where radiotherapy facilities are limited. View Full-Text
Keywords: cervical cancer; International Federation of Gynecology and Obstetrics; postoperative adjuvant therapy; systemic chemotherapy; concurrent chemoradiotherapy cervical cancer; International Federation of Gynecology and Obstetrics; postoperative adjuvant therapy; systemic chemotherapy; concurrent chemoradiotherapy
Show Figures

Figure 1

MDPI and ACS Style

Kagabu, M.; Nagasawa, T.; Tatsuki, S.; Fukagawa, Y.; Tomabechi, H.; Takatori, E.; Kaido, Y.; Shoji, T.; Baba, T. Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study. Medicina 2021, 57, 548. https://doi.org/10.3390/medicina57060548

AMA Style

Kagabu M, Nagasawa T, Tatsuki S, Fukagawa Y, Tomabechi H, Takatori E, Kaido Y, Shoji T, Baba T. Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study. Medicina. 2021; 57(6):548. https://doi.org/10.3390/medicina57060548

Chicago/Turabian Style

Kagabu, Masahiro, Takayuki Nagasawa, Shunsuke Tatsuki, Yasuko Fukagawa, Hidetoshi Tomabechi, Eriko Takatori, Yoshitaka Kaido, Tadahiro Shoji, and Tsukasa Baba. 2021. "Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study" Medicina 57, no. 6: 548. https://doi.org/10.3390/medicina57060548

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop