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Clinical Profile and Aspects of Differential Diagnosis in Patients with ME/CFS from Latvia

Turning a Corner in ME/CFS Research

Society and Health, Buckinghamshire New University, High Wycombe HP11 2JZ, UK
School of Osteopathic Medicine, Rowan University, Stratford, NJ 08080, USA
Institute of Microbiology and Virology, Riga Stradiņš University, LV-1067 Riga, Latvia
Department of Exercise Physiology and Functional Anatomy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Swietojanska 20, 85-077 Bydgoszcz, Poland
Author to whom correspondence should be addressed.
Medicina 2021, 57(10), 1012;
Received: 16 September 2021 / Accepted: 20 September 2021 / Published: 25 September 2021
(This article belongs to the Special Issue ME/CFS: Causes, Clinical Features and Diagnosis)
This collection of research papers addresses fundamental questions concerning the nature of myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS), the problem of disbelief and lack of knowledge and understanding of the condition among many doctors and the origins of this problem, and its impact on patients and their families. We report briefly the growing knowledge of the underlying pathological processes in ME/CFS, and the development of new organizations, including Doctors with ME, the US ME/CFS Clinical Coalition and EUROMENE, to address aspects of the challenges posed by the illness. We discuss the implications of COVID-19, which has much in common with ME/CFS, with much overlap of symptoms, and propose a new taxonomic category, which we are terming post-active phase of infection syndromes (PAPIS) to include both. This collection of papers includes a number of papers reporting similar serious impacts on the quality of life of patients and their families in various European countries. The advice of EUROMENE experts on diagnosis and management is included in the collection. We report this in light of guidance from other parts of the world, including the USA and Australia, and in the context of current difficulties in the UK over the promulgation of a revised guideline from the National Institute for Health and Care Excellence (NICE). We also consider evidence on the cost-effectiveness of interventions for ME/CFS, and on the difficulties of determining the costs of care when a high proportion of people with ME/CFS are never diagnosed as such. The Special Issue includes a paper which is a reminder of the importance of a person-centred approach to care by reviewing mind–body interventions. Finally, another paper reviews the scope for prevention in minimizing the population burden of ME/CFS, and concludes that secondary prevention, through early detection and diagnosis, could be of value. View Full-Text
Keywords: ME/CFS; myalgic encephalomyelitis; chronic fatigue syndrome; knowledge and understanding; quality of life; guideline; clinical care ME/CFS; myalgic encephalomyelitis; chronic fatigue syndrome; knowledge and understanding; quality of life; guideline; clinical care
MDPI and ACS Style

Pheby, D.F.H.; Friedman, K.J.; Murovska, M.; Zalewski, P. Turning a Corner in ME/CFS Research. Medicina 2021, 57, 1012.

AMA Style

Pheby DFH, Friedman KJ, Murovska M, Zalewski P. Turning a Corner in ME/CFS Research. Medicina. 2021; 57(10):1012.

Chicago/Turabian Style

Pheby, Derek F.H., Kenneth J. Friedman, Modra Murovska, and Pawel Zalewski. 2021. "Turning a Corner in ME/CFS Research" Medicina 57, no. 10: 1012.

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