Nutritional Aspects in Diabetic CKD Patients on Tertiary Care
Abstract
:1. Introduction
2. Materials and Methods
2.1. Biochemistry
2.2. Anthropometry
2.3. Resting Energy Expenditure
2.4. Physical Activity and Performance
2.5. Functional Tests
2.6. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Diabetic CKD | Nondiabetic CKD | p Value | |
---|---|---|---|
Gender, m/f | 40/8 | 80/16 | |
Age, yrs | 71.5 ± 8.2 | 71.6 ± 9 | 0.875 |
eGFR, ml/min×1.73 m2 | 29.8 ± 9.1 | 31.3 ± 10.9 | 0.398 |
BUN, mg/dL | 43 ± 16 | 37.6 ± 12.2 | 0.044 |
sCreatinine, mg/dL | 2.26 (1.77–2.78) | 2.10 (1.68–2.82) | 0.596 |
sSodium, mEq/L | 141 (140–142) | 140 (139–142) | 0.843 |
sPotassium, mEq/L | 4.78 ± 0.52 | 4.70 ± 0.52 | 0.406 |
sCalcium, mg/dL | 9.33 ± 0.41 | 9.29 ± 0.48 | 0.602 |
sPhosphate, mg/dL | 3.34 ± 0.63 | 3.33 ± 0.56 | 0.915 |
Bicarbonate, mEq/L | 25.4 ± 3.7 | 24.7 ± 2.7 | 0.354 |
sTotal Protein, g/dL | 7.10 ± 0.48 | 7.14 ± 0.47 | 0.614 |
sAlbumin, g/dL | 4.18 ± 0.45 | 4.16 ± 0.38 | 0.762 |
Hemoglobin, g/dL | 13.1 ± 1.7 | 13.2 ± 1.6 | 0.743 |
Hematocrit, % | 38.8 ± 5.8 | 39.7 ± 4.5 | 0.332 |
25(OH)VitD, ng/mL | 20.5 ± 10.3 | 22.4 ± 10.9 | 0.398 |
sCholesterol, mg/dL | 170 ± 38 | 179 ± 39 | 0.197 |
Diabetic CKD n = 48 | Nondiabetic CKD n = 96 | p Value | |
---|---|---|---|
Body weight, kg | 83.1 ± 15 | 76.4 ± 12.3 | 0.0090 |
BMI, kg/m2 | 29.1 ± 4.64 | 27.2 ± 3.52 | 0.0144 |
Waist circ., cm | 104.7 ± 11.9 | 99.4 ± 12.4 | 0.0162 |
MAMC, cm | 26.0 ± 4.2 | 25.3 ± 10 | 0.5581 |
MAMA, cm2 | 55.4 ± 16.9 | 58.9 ± 86.5 | 0.7030 |
Phase angle, ° | 5 ± 1 | 4.9 ± 1 | 0.8655 |
BCMI, kg/m2 | 9.5 ± 1.9 | 9.4 ± 2.9 | 0.8423 |
FM, % | 31.5 ± 7.4 | 27.8 ± 6.7 | 0.0071 |
MM, % | 40.1 ± 5.3 | 43.2 ± 5.7 | 0.0324 |
Average daily Mets | 1.17 ± 0.2 | 1.29 ± 0.2 | 0.0167 |
Average daily steps | 3580 ± 2471 | 5628 ± 4143 | 0.0080 |
6MWT, m | 318 ± 94 | 331 ± 84 | 0.4839 |
Hand grip, kg | 29.1 ± 7.5 | 26.5 ± 7.9 | 0.0602 |
REE, kcal/d | 1341 (1231–1531) | 1224 (1150–1468) | 0.012 |
nPCR, g/kg b.w/d | 0.86 ± 0.22 | 0.81 ± 0.19 | 0.3481 |
Univariate Analysis | eGFR Adjusted | ||
---|---|---|---|
HR (CI 95%) | p Value | p Value | |
Diabetes, (0) no; (1) yes | 1.26 (0.62–2.57) | 0.691 | 0.414 |
MAMC, cm | 0.85 (0.78–0.91) | <0.001 | <0.001 |
Phase angle, ° | 0.67 (0.46–0.98) | 0.041 | 0.025 |
BCM, kg | 0.95 (0.89–1.01) | 0.125 | 0.184 |
FFM, kg | 0.99 (0.95–1.02) | 0.475 | 0.963 |
Urea, mg/dL | 1.03 (1.02–1.04) | <0.001 | 0.088 |
Phosphate, mg/dL | 3.20 (1.61–6.34) | 0.001 | 0.082 |
Total cholesterol, mg/dL | 0.98 (0.97–0.99) | 0.001 | <0.001 |
sAlbumin, g/dL | 0.24 (0.09–0.66) | 0.005 | 0.024 |
Hemoglobin, g/dL | 0.66 (0.51–0.86) | 0.002 | 0.072 |
Hematocrit, % | 0.95 (0.90–0.97) | 0.034 | 0.221 |
nPCR*, g/kg b.w/d | 0.13 (0.01–1.55) | 0.106 | 0.768 |
6MWT, m | 0.98 (0.99–1.01) | 0.203 | 0.373 |
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D’Alessandro, C.; Barsotti, M.; Cianchi, C.; Mannucci, C.; Morganti, R.; Tassi, S.; Cupisti, A. Nutritional Aspects in Diabetic CKD Patients on Tertiary Care. Medicina 2019, 55, 427. https://doi.org/10.3390/medicina55080427
D’Alessandro C, Barsotti M, Cianchi C, Mannucci C, Morganti R, Tassi S, Cupisti A. Nutritional Aspects in Diabetic CKD Patients on Tertiary Care. Medicina. 2019; 55(8):427. https://doi.org/10.3390/medicina55080427
Chicago/Turabian StyleD’Alessandro, Claudia, Massimiliano Barsotti, Caterina Cianchi, Claudia Mannucci, Riccardo Morganti, Serena Tassi, and Adamasco Cupisti. 2019. "Nutritional Aspects in Diabetic CKD Patients on Tertiary Care" Medicina 55, no. 8: 427. https://doi.org/10.3390/medicina55080427