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Sensors 2009, 9(12), 9896-9902; https://doi.org/10.3390/s91209896

All-Plastic Electrochemical Transistor for Glucose Sensing Using a Ferrocene Mediator

1
Materials Science and Engineering, Cornell University, Ithaca, NY 14853, USA
2
Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA
3
Centre Microélectronique de Provence, Ecole Nationale Supérieure des Mines de Saint Etienne, 13541 Gardanne, France
*
Author to whom correspondence should be addressed.
Received: 19 October 2009 / Revised: 25 November 2009 / Accepted: 27 November 2009 / Published: 4 December 2009
(This article belongs to the Section Biosensors)
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Abstract

We demonstrate a glucose sensor based on an organic electrochemical transistor (OECT) in which the channel, source, drain, and gate electrodes are made from the conducting polymer poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate) (PEDOT:PSS). The OECT employs a ferrocene mediator to shuttle electrons between the enzyme glucose oxidase and a PEDOT:PSS gate electrode. The device can be fabricated using a one-layer patterning process and offers glucose detection down to the micromolar range, consistent with levels present in human saliva. View Full-Text
Keywords: organic electrochemical transistor; glucose sensor; ferrocene mediator organic electrochemical transistor; glucose sensor; ferrocene mediator
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Shim, N.Y.; Bernards, D.A.; Macaya, D.J.; DeFranco, J.A.; Nikolou, M.; Owens, R.M.; Malliaras, G.G. All-Plastic Electrochemical Transistor for Glucose Sensing Using a Ferrocene Mediator. Sensors 2009, 9, 9896-9902.

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