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Sensors, Volume 4, Issue 4 (April 2004) – 3 articles , Pages 18-46

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Open AccessArticle
Mathematical Model of the Biosensors Acting in a Trigger Mode
Sensors 2004, 4(4), 20-36; https://doi.org/10.3390/s40400020 - 26 May 2004
Cited by 10 | Viewed by 4826
Abstract
A mathematical model of biosensors acting in a trigger mode has been developed. One type of the biosensors utilized a trigger enzymatic reaction followed by the cyclic enzymatic and electrochemical conversion of the product (CCE scheme). Other biosensors used the enzymatic trigger reaction [...] Read more.
A mathematical model of biosensors acting in a trigger mode has been developed. One type of the biosensors utilized a trigger enzymatic reaction followed by the cyclic enzymatic and electrochemical conversion of the product (CCE scheme). Other biosensors used the enzymatic trigger reaction followed by the electrochemical and enzymatic product cyclic conversion (CEC scheme). The models were based on diffusion equations containing a non-linear term related to Michaelis-Menten kinetics of the enzymatic reactions. The digital simulation was carried out using the finite difference technique. The influence of the substrate concentration, the maximal enzymatic rate as well as the membrane thickness on the biosensor response was investigated. The numerical experiments demonstrated a significant gain (up to dozens of times) in biosensor sensitivity when the biosensor response was under diffusion control. In the case of significant signal amplification, the response time with triggering was up to several times longer than that of the biosensor without triggering. Full article
Open AccessArticle
Temperature Gradient Effect on Gas Discrimination Power of a Metal-Oxide Thin-Film Sensor Microarray
Sensors 2004, 4(4), 37-46; https://doi.org/10.3390/s40400037 - 18 May 2004
Cited by 47 | Viewed by 6380
Abstract
The paper presents results concerning the effect of spatial inhomogeneous operating temperature on the gas discrimination power of a gas-sensor microarray, with the latter based on a thin SnO2 film employed in the KAMINA electronic nose. Three different temperature distributions over the substrate [...] Read more.
The paper presents results concerning the effect of spatial inhomogeneous operating temperature on the gas discrimination power of a gas-sensor microarray, with the latter based on a thin SnO2 film employed in the KAMINA electronic nose. Three different temperature distributions over the substrate are discussed: a nearly homogeneous one and two temperature gradients, equal to approx. 3.3 oC/mm and 6.7 oC/mm, applied across the sensor elements (segments) of the array. The gas discrimination power of the microarray is judged by using the Mahalanobis distance in the LDA (Linear Discrimination Analysis) coordinate system between the data clusters obtained by the response of the microarray to four target vapors: ethanol, acetone, propanol and ammonia. It is shown that the application of a temperature gradient increases the gas discrimination power of the microarray by up to 35 %. Full article
Open AccessEditorial
New Editor-in-Chief of Sensors
Sensors 2004, 4(4), 18-19; https://doi.org/10.3390/s40400018 - 12 Apr 2004
Cited by 37 | Viewed by 3022
Abstract
I would like to introduce myself as the new Editor-in-Chief of Sensors: Born in Bruchsal, Germany, I received my diploma in electrical engineering in 1989 and my doctoral degree (Ph.D.) in 1993, both from the Technical University (TH) Karlsruhe.[...] Full article
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