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Open AccessArticle

Analysis of Human Breath by Millimeter-Wave/Terahertz Spectroscopy

1
Institute of Optical Sensor Systems, German Aerospace Center (DLR), 12489 Berlin, Germany
2
Department of Physics, Humboldt-Universität zu Berlin, 12489 Berlin, Germany
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Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), 30625 Hannover, Germany
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The German Center for Lung Research (DZL), 35043 Marburg/35392 Giessen, Germany
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Department of Pulmonology, Institute for Internal Medicine, Philipps-University of Marburg, 35043 Marburg, Germany
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Schön Klinik Berchtesgadener Land, Department for Pulmonology, Teaching Hospital of the Philipps-University, 35043 Marburg, Germany
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Teaching Department of the Paracelsus University Salzburg, 5020 Salzburg, Austria
8
IHP—Leibniz-Institut für innovative Mikroelektronik, 15236 Frankfurt (Oder), Germany
*
Author to whom correspondence should be addressed.
Sensors 2019, 19(12), 2719; https://doi.org/10.3390/s19122719
Received: 8 May 2019 / Revised: 12 June 2019 / Accepted: 13 June 2019 / Published: 17 June 2019
(This article belongs to the Section Biosensors)
Breath gas analysis is a promising tool for medical research and diagnosis. A particularly powerful technological approach is millimeter-wave/terahertz (mmW/THz) spectroscopy, because it is a very sensitive and highly selective technique. In addition, it offers the potential for compact and affordable sensing systems for wide use. In this work, we demonstrate the capability of a mmW/THz spectrometer for breath analysis. Samples from three volunteers and a sample from ambient air were analyzed with respect to 31 different molecular species. High-resolution absorption spectra were measured by scanning two absorption lines from each species. Out of the 31, a total of 21 species were detected. The results demonstrate the potential of mmW/THz spectroscopy for breath analysis. View Full-Text
Keywords: breath analysis; millimeter-wave; terahertz; spectroscopy; molecular spectroscopy; gas sensing breath analysis; millimeter-wave; terahertz; spectroscopy; molecular spectroscopy; gas sensing
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MDPI and ACS Style

Rothbart, N.; Holz, O.; Koczulla, R.; Schmalz, K.; Hübers, H.-W. Analysis of Human Breath by Millimeter-Wave/Terahertz Spectroscopy. Sensors 2019, 19, 2719.

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