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Sensors 2016, 16(3), 285;

Last Advances in Silicon-Based Optical Biosensors

Nanobiosensors and Bioanalytical Applications Group. Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, The Barcelona Institute of Science and Technology and CIBER-BBN, Campus UAB, Ed-ICN2, 08193 Bellaterra, Barcelona, Spain
School of Electrical and Computer Engineering (FEEC), University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil
Author to whom correspondence should be addressed.
Academic Editor: Alexander Star
Received: 9 November 2015 / Revised: 25 January 2016 / Accepted: 18 February 2016 / Published: 24 February 2016
(This article belongs to the Section Biosensors)
Full-Text   |   PDF [2725 KB, uploaded 24 February 2016]   |  


We review the most important achievements published in the last five years in the field of silicon-based optical biosensors. We focus specially on label-free optical biosensors and their implementation into lab-on-a-chip platforms, with an emphasis on developments demonstrating the capability of the devices for real bioanalytical applications. We report on novel transducers and materials, improvements of existing transducers, new and improved biofunctionalization procedures as well as the prospects for near future commercialization of these technologies. View Full-Text
Keywords: photonic biosensors; label-free detection; silicon photonics; waveguide devices photonic biosensors; label-free detection; silicon photonics; waveguide devices

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Fernández Gavela, A.; Grajales García, D.; Ramirez, J.C.; Lechuga, L.M. Last Advances in Silicon-Based Optical Biosensors. Sensors 2016, 16, 285.

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