Next Article in Journal
An Effective Correction Method for Seriously Oblique Remote Sensing Images Based on Multi-View Simulation and a Piecewise Model
Next Article in Special Issue
Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
Previous Article in Journal
Effectiveness Testing of a Piezoelectric Energy Harvester for an Automobile Wheel Using Stochastic Resonance
Previous Article in Special Issue
Mid-Infrared Photoacoustic Detection of Glucose in Human Skin: Towards Non-Invasive Diagnostics
Article Menu

Export Article

Open AccessArticle
Sensors 2016, 16(10), 1720;

Non-Enzymatic Glucose Sensing Using Carbon Quantum Dots Decorated with Copper Oxide Nanoparticles

Institut d’Electronique, de Microélectronique et de Nanotechnologie (IEMN), UMR CNRS8520, Université Lille 1, Avenue Poincaré-BP 60069, 59652 Villeneuve d’Ascq, France
Département de Physique, Faculté des Sciences de Tunis, Université Tunis-El Manar, 2092 Tunis, Tunisia
State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, 3888 Dong Nanhu Road, 130033 Changchun, China
Unité Matériaux et transformations (UMET), UMR CNRS 8207, Université Lille1, Cité Scientifique, 59655 Villeneuve d’Ascq, France
Author to whom correspondence should be addressed.
Academic Editors: Giovanni Sparacino, Andrea Facchinetti and J. Hans DeVries
Received: 13 August 2016 / Revised: 7 October 2016 / Accepted: 12 October 2016 / Published: 18 October 2016
(This article belongs to the Special Issue Glucose Sensors: Revolution in Diabetes Management 2016)
Full-Text   |   PDF [2105 KB, uploaded 18 October 2016]   |  


Perturbations in glucose homeostasis is critical for human health, as hyperglycemia (defining diabetes) leads to premature death caused by macrovascular and microvascular complications. However, the simple and accurate detection of glucose in the blood at low cost remains a challenging task, although it is of great importance for the diagnosis and therapy of diabetic patients. In this work, carbon quantum dots decorated with copper oxide nanostructures (CQDs/Cu2O) are prepared by a simple hydrothermal approach, and their potential for electrochemical non-enzymatic glucose sensing is evaluated. The proposed sensor exhibits excellent electrocatalytic activity towards glucose oxidation in alkaline solutions. The glucose sensor is characterized by a wide concentration range from 6 µM to 6 mM, a sensitivity of 2.9 ± 0.2 µA·µM−1·cm−2, and a detection limit of 6 µM at a signal-to-noise ratio S/N = 3. The sensors are successfully applied for glucose determination in human serum samples, demonstrating that the CQDs/Cu2O-based glucose sensor satisfies the requirements of complex sample detection with adapted potential for therapeutic diagnostics. View Full-Text
Keywords: carbon quantum dots; copper oxide nanoparticles; glucose sensing; non-enzymatic; serum; electrochemistry carbon quantum dots; copper oxide nanoparticles; glucose sensing; non-enzymatic; serum; electrochemistry

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Maaoui, H.; Teodoresu, F.; Wang, Q.; Pan, G.-H.; Addad, A.; Chtourou, R.; Szunerits, S.; Boukherroub, R. Non-Enzymatic Glucose Sensing Using Carbon Quantum Dots Decorated with Copper Oxide Nanoparticles. Sensors 2016, 16, 1720.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top