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Sensors 2016, 16(10), 1736;

Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery

Supramolecular Chemistry Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, Ghent 9000, Belgium
Author to whom correspondence should be addressed.
Academic Editors: Giovanni Sparacino, Andrea Facchinetti and J. Hans DeVries
Received: 4 September 2016 / Revised: 11 October 2016 / Accepted: 13 October 2016 / Published: 19 October 2016
(This article belongs to the Special Issue Glucose Sensors: Revolution in Diabetes Management 2016)
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Boronic acid-containing (co)polymers have fascinated researchers for decades, garnering attention for their unique responsiveness toward 1,2- and 1,3-diols, including saccharides and nucleotides. The applications of materials that exert this property are manifold including sensing, but also self-regulated drug delivery systems through responsive membranes or micelles. In this review, some of the main applications of boronic acid containing (co)polymers are discussed focusing on the role of the boronic acid group in the response mechanism. We hope that this summary, which highlights the importance and potential of boronic acid-decorated polymeric materials, will inspire further research within this interesting field of responsive polymers and polymeric materials. View Full-Text
Keywords: boronic acid; glucose-responsive; self-assembly; polymers; drug delivery boronic acid; glucose-responsive; self-assembly; polymers; drug delivery

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Vancoillie, G.; Hoogenboom, R. Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery. Sensors 2016, 16, 1736.

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