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Molbank 2019, 2019(1), M1040; https://doi.org/10.3390/M1040

2′-Chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine

1
Applied Science Department, University of Technology, Baghdad 10001, Iraq
2
Pharmaceutical Chemistry Department, College of Pharmacy, University of Kufa, AL-Najaf 31001, Iraq
3
Energy and Renewable Energies Technology Center, University of Technology, Baghdad 10001, Iraq
*
Authors to whom correspondence should be addressed.
Received: 17 November 2018 / Revised: 29 November 2018 / Accepted: 9 December 2018 / Published: 22 December 2018
(This article belongs to the Special Issue Metal-Catalyzed Synthesis)
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Abstract

The compound 2′-chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine was obtained with a good yield by the reaction of 2-chloro-4-(1-methyl-1H-imidazol-2-yl)pyridine with (2-chloropyridin-4-yl)boronic acid and structurally characterized by nuclear magnetic resonance (1H-NMR and 13C-NMR), thin-layer chromatography–mass spectrometry (TLC–MS), HPLC, gas chromatography–mass spectrometry (GC–MS), and elemental analysis. The functionalization of the pyridine was achieved by the palladium-catalyzed Suzuki–Miyaura carbon–carbon cross-coupling reaction that afforded the target compound. View Full-Text
Keywords: Suzuki–Miyaura; imidazole; boronic acid; palladium-catalyzed; mass spectrometry Suzuki–Miyaura; imidazole; boronic acid; palladium-catalyzed; mass spectrometry
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Zinad, D.S.; AL-Duhaidahaw, D.L.; Al-Amiery, A. 2′-Chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine. Molbank 2019, 2019, M1040.

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