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Open AccessShort Note

2′-Chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine

1
Applied Science Department, University of Technology, Baghdad 10001, Iraq
2
Pharmaceutical Chemistry Department, College of Pharmacy, University of Kufa, AL-Najaf 31001, Iraq
3
Energy and Renewable Energies Technology Center, University of Technology, Baghdad 10001, Iraq
*
Authors to whom correspondence should be addressed.
Molbank 2019, 2019(1), M1040; https://doi.org/10.3390/M1040
Received: 17 November 2018 / Revised: 29 November 2018 / Accepted: 9 December 2018 / Published: 22 December 2018
(This article belongs to the Special Issue Metal-Catalyzed Synthesis)
The compound 2′-chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine was obtained with a good yield by the reaction of 2-chloro-4-(1-methyl-1H-imidazol-2-yl)pyridine with (2-chloropyridin-4-yl)boronic acid and structurally characterized by nuclear magnetic resonance (1H-NMR and 13C-NMR), thin-layer chromatography–mass spectrometry (TLC–MS), HPLC, gas chromatography–mass spectrometry (GC–MS), and elemental analysis. The functionalization of the pyridine was achieved by the palladium-catalyzed Suzuki–Miyaura carbon–carbon cross-coupling reaction that afforded the target compound. View Full-Text
Keywords: Suzuki–Miyaura; imidazole; boronic acid; palladium-catalyzed; mass spectrometry Suzuki–Miyaura; imidazole; boronic acid; palladium-catalyzed; mass spectrometry
MDPI and ACS Style

Zinad, D.S.; AL-Duhaidahaw, D.L.; Al-Amiery, A. 2′-Chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine. Molbank 2019, 2019, M1040.

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