AbstractA new compound (E)-3-[3-(4-morpholinophenyl)acryloyl]-2H-chromen-2-one, a coumarin based chalcone derivative, has been successfully synthesized employing a molecular hybridization method through the reaction between 3-acetylcoumarin and 4-morpholinobenzaldehyde using a Claisen–Schmidt reaction using pTSA as a catalyst. The structure of the title compound was established using spectroscopic data FTIR, HRESI-MS, 1H- and 13C-NMR. The anticancer activity against breast cancer cells line T47D and cervix cancer cells line HeLa was determined using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. View Full-Text
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Suwito, H.; Hardiyanti, H.D.; Ul Haq, K.; Kristanti, A.N.; Khasanah, M. (E)-3-[3-(4-Morpholinophenyl)acryloyl]-2H-chromen-2-one. Molbank 2018, 2018, M1027.
Suwito H, Hardiyanti HD, Ul Haq K, Kristanti AN, Khasanah M. (E)-3-[3-(4-Morpholinophenyl)acryloyl]-2H-chromen-2-one. Molbank. 2018; 2018(4):M1027.Chicago/Turabian Style
Suwito, Hery; Hardiyanti, Helda D.; Ul Haq, Kautsar; Kristanti, Alfinda N.; Khasanah, Miratul. 2018. "(E)-3-[3-(4-Morpholinophenyl)acryloyl]-2H-chromen-2-one." Molbank 2018, no. 4: M1027.
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