Next Article in Journal
Protective Effect of Probiotics against Pseudomonas aeruginosa Infection of Human Corneal Epithelial Cells
Previous Article in Journal
Fluorescence-Based Protein Stability Monitoring—A Review
Previous Article in Special Issue
Contribution of the Surface Treatment of Nanofibrillated Cellulose on the Properties of Bio-Based Epoxy Nanocomposites Intended for Flexible Electronics
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 25
Issue 3
10.3390/ijms25031768
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Wet-Spun Chitosan–Sodium Caseinate Fibers for Biomedicine: From Spinning Process to Physical Properties

by
Hazel Peniche
1,2,
Ivy Ann Razonado
1,
Pierre Alcouffe
1,
Guillaume Sudre
1,
Carlos Peniche
3,
Anayancy Osorio-Madrazo
4,5,* and
Laurent David
1,*
1
Ingénierie des Matériaux Polymères (IMP), Universite Claude Bernard Lyon 1, INSA de Lyon, Universite J. Monnet, CNRS, UMR 5223, 69622 Villeurbanne CEDEX, France
2
Biomaterials Center, University of Havana, Havana 10600, Cuba
3
Faculty of Chemistry, University of Havana, Havana 10600, Cuba
4
Laboratory of Organic and Macromolecular Chemistry (IOMC), Jena Center for Soft Matter (JCSM), and Center for Energy and Environmental Chemistry Jena (CEEC), Friedrich Schiller University of Jena, 07743 Jena, Germany
5
Laboratory of Organ Printing, University of Bayreuth, 95447 Bayreuth, Germany
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2024, 25(3), 1768; https://doi.org/10.3390/ijms25031768
Submission received: 9 December 2023 / Revised: 24 January 2024 / Accepted: 27 January 2024 / Published: 1 February 2024
(This article belongs to the Special Issue Polymeric Materials from Chemistry, Functional and Biological Characterization to Applications)
Browse Figures
Review Reports Versions Notes

Abstract

We designed and characterized chitosan–caseinate fibers processed through wet spinning for biomedical applications such as drug delivery from knitted medical devices. Sodium caseinate was either incorporated directly into the chitosan dope or allowed to diffuse into the chitosan hydrogel from a coagulation bath containing sodium caseinate and sodium hydroxide (NaOH). The latter route, where caseinate was incorporated in the neutralization bath, produced fibers with better mechanical properties for textile applications than those formed by the chitosan–caseinate mixed collodion route. The latter processing method consists of enriching a pre-formed chitosan hydrogel with caseinate, preserving the structure of the semicrystalline hydrogel without drastically affecting interactions involved in the chitosan self-assembly. Thus, dried fibers, after coagulation in a NaOH/sodium caseinate aqueous bath, exhibited preserved ultimate mechanical properties. The crystallinity ratio of chitosan was not significantly impacted by the presence of caseinate. However, when caseinate was incorporated into the chitosan dope, chitosan–caseinate fibers exhibited lower ultimate mechanical properties, possibly due to a lower entanglement density in the amorphous phase of the chitosan matrix. A standpoint is to optimize the chitosan–caseinate composition ratio and processing route to find a good compromise between the preservation of fiber mechanical properties and appropriate fiber composition for potential application in drug release.
Keywords: chitosan; casein; fiber wet spinning; mechanical properties; biomedical textiles chitosan; casein; fiber wet spinning; mechanical properties; biomedical textiles

Share and Cite

MDPI and ACS Style

Peniche, H.; Razonado, I.A.; Alcouffe, P.; Sudre, G.; Peniche, C.; Osorio-Madrazo, A.; David, L. Wet-Spun Chitosan–Sodium Caseinate Fibers for Biomedicine: From Spinning Process to Physical Properties. Int. J. Mol. Sci. 2024, 25, 1768. https://doi.org/10.3390/ijms25031768

AMA Style

Peniche H, Razonado IA, Alcouffe P, Sudre G, Peniche C, Osorio-Madrazo A, David L. Wet-Spun Chitosan–Sodium Caseinate Fibers for Biomedicine: From Spinning Process to Physical Properties. International Journal of Molecular Sciences. 2024; 25(3):1768. https://doi.org/10.3390/ijms25031768

Chicago/Turabian Style

Peniche, Hazel, Ivy Ann Razonado, Pierre Alcouffe, Guillaume Sudre, Carlos Peniche, Anayancy Osorio-Madrazo, and Laurent David. 2024. "Wet-Spun Chitosan–Sodium Caseinate Fibers for Biomedicine: From Spinning Process to Physical Properties" International Journal of Molecular Sciences 25, no. 3: 1768. https://doi.org/10.3390/ijms25031768

APA Style

Peniche, H., Razonado, I. A., Alcouffe, P., Sudre, G., Peniche, C., Osorio-Madrazo, A., & David, L. (2024). Wet-Spun Chitosan–Sodium Caseinate Fibers for Biomedicine: From Spinning Process to Physical Properties. International Journal of Molecular Sciences, 25(3), 1768. https://doi.org/10.3390/ijms25031768

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop