Clinico-Pathogenic Similarities and Differences between Infection-Related Glomerulonephritis and C3 Glomerulopathy
, Togo Aoyama 1, Takashi Oda 2 and Yasuo Takeuchi 1
Round 1
Reviewer 1 Report
Great work and thank you for clear descriptions and differentiation of the two aspects of GN disease. This would be a great source of understanding the pathophysiology of GN especially post kidney transplant nephropathy.
The quality of the English language is acceptable, but needs minor grammatical correction.
Author Response
Reviewer 1
Major comments
Great work and thank you for clear descriptions and differentiation of the two aspects of GN disease. This would be a great source of understanding the pathophysiology of GN especially post kidney transplant nephropathy.
・Comments on the Quality of English Language
The quality of the English language is acceptable, but needs minor grammatical correction.
Thank you very much for your positive comments to our manuscript. As you pointed out, we realized that minor grammatical correction is necessary. So, we asked an English proofreading company to improve our English in the manuscript. Moreover, the layout of the Table 1 and Table 2 have also been sufficiently modified.
Reviewer 2 Report
The presented review is an important work where authors try to gather avaialable literature data in order to help the differentiation of infection-related glomerulonephritis and complement C3 glomerulopathies. The work is concise, with represenatative and interesting histology / immunohistochemistry data. These figures are of very good quality. The last summary figure is especially helpful for physicians showing which markers could be considered in the differential diagnosis of the two clinical entities.
The only minor issue is the need for a thorough English grammar check-up. Singular/plural is mixed several times, as well as verbs used in indicative context can be seen sometimes ("eg: ...identified as causing proteins for...").
Author Response
Reviewer 2
Major comments
The presented review is an important work where authors try to gather avaialable literature data in order to help the differentiation of infection-related glomerulonephritis and complement C3 glomerulopathies. The work is concise, with represenatative and interesting histology / immunohistochemistry data. These figures are of very good quality. The last summary figure is especially helpful for physicians showing which markers could be considered in the differential diagnosis of the two clinical entities.
・Comments on the Quality of English Language
The only minor issue is the need for a thorough English grammar check-up. Singular/plural is mixed several times, as well as verbs used in indicative context can be seen sometimes ("eg: ...identified as causing proteins for...").
We deeply appreciate your appropriate review and sincere comments. As you pointed out, we recognized the appropriate check-up for English grammar in the manuscript to improve the quality of manuscript. Thereby, we ordered an English proofreading to let our English description in the manuscript improve.
