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Article
Peer-Review Record

Alginate Oligosaccharides Repair Liver Injury by Improving Anti-Inflammatory Capacity in a Busulfan-Induced Mouse Model

Int. J. Mol. Sci. 2023, 24(4), 3097; https://doi.org/10.3390/ijms24043097
by Yanan Hao 1,2,3,4, Hanhan Fang 2,4, Xiaowei Yan 2, Wei Shen 2, Jing Liu 5, Pengfei Han 2, Yong Zhao 3,4, Weidong Zhang 4,* and Yanni Feng 1,*
Int. J. Mol. Sci. 2023, 24(4), 3097; https://doi.org/10.3390/ijms24043097
Submission received: 13 December 2022 / Revised: 20 January 2023 / Accepted: 2 February 2023 / Published: 4 February 2023
(This article belongs to the Section Molecular Immunology)

Round 1

Reviewer 1 Report

First of all, I would like to thank you for the opportunity to review this study. 

I believe that the subject matter of this research is suitable for this journal, however I think that a couple of things need to be modified. 

Regarding the contextualisation of the study, I think it is necessary to include a greater number of current bibliographical references, both in the introduction and in the discussion. Also, add what this research contributes to the field of study. 

Likewise, the presentation of the article should be improved as a whole. Not even the font has been respected and everything seems to be placed in a chaotic way.

Author Response

Please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

1- You didn't mention the source of Alginate oligosaccharides.

2- AOS dose (10mg/kg) preparation is unclear. 

3- On what basis did you choose the AOS dose ?

4- Many abbreviations need to be clarified.

5- the supplementary material should be more organized, many data could be omitted and summarize the most crucial ones in a tabular form.

  

Author Response

Please see the attachment

Author Response File: Author Response.xlsx

Round 2

Reviewer 1 Report

Thank you very much for reviewing the research. In this case I consider that everything I quoted previously has been considerably improved. I therefore give the go-ahead for the publication of this research. 

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