Peer-Review Record
Autosomal Dominant Polycystic Kidney Disease: From Pathophysiology of Cystogenesis to Advances in the Treatment
Int. J. Mol. Sci. 2022, 23(6), 3317; https://doi.org/10.3390/ijms23063317
Reviewer 1:
Anonymous
Reviewer 2:
Anonymous
Int. J. Mol. Sci. 2022, 23(6), 3317; https://doi.org/10.3390/ijms23063317
Submission received: 18 February 2022
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Revised: 17 March 2022
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Accepted: 18 March 2022
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Published: 19 March 2022
(This article belongs to the Special Issue Molecular Pathology, Diagnostics, and Therapeutics of Nephropathy)
Round 1
Reviewer 1 Report
The article is well structured and deals with the topic well. I recommend it for publication. congratulations to the authors for their work.Author Response
We sincerely thank you for your time, and valuable suggestions to improve the manuscript.
Reviewer 2 Report
This is a well-organized and interesting review. It covers most of the latest information on the etiology and treatment of ADPKD.
- If there are some suggestions, the introduction, pathogenesis, and treatments are all described in parallel, so I think it's better to divide them into three major paragraphs.
- There is a little description about the clinical symptoms and course in the introduction, but considering the timing of the treatment described later, I think it is better to explain in a little more detail.
- It is also good to mention the relationship between these clinical symptoms and the etiology. For example, what is the mechanism by which ADPKD patients develop hypertension?
Author Response
Dear reviewer,
- I divided the manuscript in introduction, pathogenesis and treatments.
- I described clinical course in more details in introduction.
- I mentioned the pathophysiology of hypertensin in ADPKD in introduction.
Yours sincerely
Jana Reiterová
Author Response File: 
Author Response.pdf
