Next Article in Journal
A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease
Next Article in Special Issue
NMR Structure and Biophysical Characterization of Thermophilic Single-Stranded DNA Binding Protein from Sulfolobus Solfataricus
Previous Article in Journal
Green Carbon Nanostructures for Functional Composite Materials
Previous Article in Special Issue
Incorporation of a FRET Pair into a Riboswitch RNA to Measure Mg2+ Concentration and RNA Conformational Change in Cell
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 23
Issue 3
10.3390/ijms23031847
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Fractal Analysis of DNA Sequences Using Frequency Chaos Game Representation and Small-Angle Scattering

by
Eugen Mircea Anitas
1,2
1
Joint Institute for Nuclear Research, 141980 Dubna, Russia
2
Horia Hulubei, National Institute of Physics and Nuclear Engineering, 077125 Bucharest, Romania
Int. J. Mol. Sci. 2022, 23(3), 1847; https://doi.org/10.3390/ijms23031847
Submission received: 16 January 2022 / Revised: 3 February 2022 / Accepted: 4 February 2022 / Published: 6 February 2022
(This article belongs to the Special Issue Biophysical Study of the Structure, Dynamics, and Function of Nucleic Acids 2.0)
Browse Figures
Versions Notes

Abstract

The fractal characteristics of DNA sequences are studied using the frequency chaos game representation (FCGR) and small-angle scattering (SAS) technique. The FCGR allows representation of the frequencies of occurrence of k-mers (oligonucleotides of length k) in the form of images. The numerically encoded data are then used in a SAS analysis to enhance hidden features in DNA sequences. It is shown that the simulated SAS intensity allows us to obtain the fractal dimensions and scaling factors at various scales. These structural parameters can be used to distinguish unambiguously between the scaling properties of complex hierarchical DNA sequences. The validity of this approach is illustrated on several sequences from: Escherichia coli, Mouse mitochondrion, Homo sapiens mitochondrion and Human cosmid.
Keywords: DNA sequences; time series; chaos game representation; multifractals; small-angle scattering DNA sequences; time series; chaos game representation; multifractals; small-angle scattering

Share and Cite

MDPI and ACS Style

Anitas, E.M. Fractal Analysis of DNA Sequences Using Frequency Chaos Game Representation and Small-Angle Scattering. Int. J. Mol. Sci. 2022, 23, 1847. https://doi.org/10.3390/ijms23031847

AMA Style

Anitas EM. Fractal Analysis of DNA Sequences Using Frequency Chaos Game Representation and Small-Angle Scattering. International Journal of Molecular Sciences. 2022; 23(3):1847. https://doi.org/10.3390/ijms23031847

Chicago/Turabian Style

Anitas, Eugen Mircea. 2022. "Fractal Analysis of DNA Sequences Using Frequency Chaos Game Representation and Small-Angle Scattering" International Journal of Molecular Sciences 23, no. 3: 1847. https://doi.org/10.3390/ijms23031847

APA Style

Anitas, E. M. (2022). Fractal Analysis of DNA Sequences Using Frequency Chaos Game Representation and Small-Angle Scattering. International Journal of Molecular Sciences, 23(3), 1847. https://doi.org/10.3390/ijms23031847

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop