TULA-Family Regulators of Platelet Activation
Abstract
:1. Novel Family of Atypical Protein Tyrosine Phosphatases
2. PTP Activities of TULA-Family Proteins and Their Possible PTP-Independent Functions
3. Regulatory Effect of TULA-2 on Platelet Signaling and Activation
3.1. Effects of TULA-Family Proteins in Cells Other Than Platelets
3.2. Effects of TULA-2 on Signaling Mediated by the Glycoprotein VI (GPVI) Collagen Receptor
3.3. Effects of TULA-2 on Signaling through FcγRIIA, A Receptor for the Fc Fragment of IgG
3.4. Effects of TULA-2 on Signaling through the C-Type Lectin-like (CLEC)-2 Receptor
3.5. Physiological Consequences of TULA-2-Mediated Signaling Regulation
4. Molecular Basis of the Regulatory Effect of TULA-2 on Platelet Signaling and Activation
5. Regulation of TULA-2 Level and Activity in Platelets
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Kunapuli, S.P.; Tsygankov, A.Y. TULA-Family Regulators of Platelet Activation. Int. J. Mol. Sci. 2022, 23, 14910. https://doi.org/10.3390/ijms232314910
Kunapuli SP, Tsygankov AY. TULA-Family Regulators of Platelet Activation. International Journal of Molecular Sciences. 2022; 23(23):14910. https://doi.org/10.3390/ijms232314910
Chicago/Turabian StyleKunapuli, Satya P., and Alexander Y. Tsygankov. 2022. "TULA-Family Regulators of Platelet Activation" International Journal of Molecular Sciences 23, no. 23: 14910. https://doi.org/10.3390/ijms232314910