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Volume 23
Issue 16
10.3390/ijms23168980
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Review

Immunomodulatory Properties of Polysaccharides from Lentinula edodes

by
Aleksander Roszczyk
1,
Jadwiga Turło
2,
Radosław Zagożdżon
1 and
Beata Kaleta
1,*
1
Department of Clinical Immunology, Medical University of Warsaw, Nowogrodzka 59, 02-006 Warsaw, Poland
2
Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2022, 23(16), 8980; https://doi.org/10.3390/ijms23168980
Submission received: 5 July 2022 / Revised: 9 August 2022 / Accepted: 10 August 2022 / Published: 11 August 2022
(This article belongs to the Special Issue The Role of Natural Products in Immunopharmacology)
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Abstract

Lentinula edodes (Berk.) Pegler, also known as shiitake mushroom, is a popular edible macrofungus and a source of numerous bioactive substances with multiple beneficial health effects. L. edodes-derived polysaccharides are the most valuable compounds, with anticancer, antioxidant, antimicrobial, and immunomodulatory properties. It has been demonstrated that their biological activity depends on the extraction method, which affects monosaccharide composition, molecular weight, branching degrees, and helical conformation. In this review, we discuss the immunomodulatory properties of various polysaccharides from L. edodes in animal models and in humans.
Keywords: immunomodulation; Lentinula edodes; polysaccharide immunomodulation; Lentinula edodes; polysaccharide

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MDPI and ACS Style

Roszczyk, A.; Turło, J.; Zagożdżon, R.; Kaleta, B. Immunomodulatory Properties of Polysaccharides from Lentinula edodes. Int. J. Mol. Sci. 2022, 23, 8980. https://doi.org/10.3390/ijms23168980

AMA Style

Roszczyk A, Turło J, Zagożdżon R, Kaleta B. Immunomodulatory Properties of Polysaccharides from Lentinula edodes. International Journal of Molecular Sciences. 2022; 23(16):8980. https://doi.org/10.3390/ijms23168980

Chicago/Turabian Style

Roszczyk, Aleksander, Jadwiga Turło, Radosław Zagożdżon, and Beata Kaleta. 2022. "Immunomodulatory Properties of Polysaccharides from Lentinula edodes" International Journal of Molecular Sciences 23, no. 16: 8980. https://doi.org/10.3390/ijms23168980

APA Style

Roszczyk, A., Turło, J., Zagożdżon, R., & Kaleta, B. (2022). Immunomodulatory Properties of Polysaccharides from Lentinula edodes. International Journal of Molecular Sciences, 23(16), 8980. https://doi.org/10.3390/ijms23168980

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