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Review

Epigenetics of Cutaneous Sarcoma

Department of Dermatology, University of Occupational and Environmental Health, 1-1, Iseigaoka, Yahatanishi-Ku, Kitakyushu 807-8555, Japan
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Author to whom correspondence should be addressed.
Academic Editors: Satoshi Kishigami and Rossella Rota
Int. J. Mol. Sci. 2022, 23(1), 422; https://doi.org/10.3390/ijms23010422
Received: 16 November 2021 / Revised: 25 December 2021 / Accepted: 28 December 2021 / Published: 31 December 2021
(This article belongs to the Special Issue Epigenetic and Transcriptional Networks in Soft Tissue Sarcomas)
Epigenetic changes influence various physiological and pathological conditions in the human body. Recent advances in epigenetic studies of the skin have led to an appreciation of the importance of epigenetic modifications in skin diseases. Cutaneous sarcomas are intractable skin cancers, and there are no curative therapeutic options for the advanced forms of cutaneous sarcomas. In this review, we discuss the detailed molecular effects of epigenetic modifications on skin sarcomas, such as dermatofibrosarcoma protuberans, angiosarcoma, Kaposi’s sarcoma, leiomyosarcoma, and liposarcoma. We also discuss the application of epigenetic-targeted therapy for skin sarcomas. View Full-Text
Keywords: skin sarcoma; epigenetics; dermatofibrosarcoma protuberans; angiosarcoma; Kaposi’s sarcoma; leiomyosarcoma; liposarcoma skin sarcoma; epigenetics; dermatofibrosarcoma protuberans; angiosarcoma; Kaposi’s sarcoma; leiomyosarcoma; liposarcoma
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MDPI and ACS Style

Mashima, E.; Sawada, Y. Epigenetics of Cutaneous Sarcoma. Int. J. Mol. Sci. 2022, 23, 422. https://doi.org/10.3390/ijms23010422

AMA Style

Mashima E, Sawada Y. Epigenetics of Cutaneous Sarcoma. International Journal of Molecular Sciences. 2022; 23(1):422. https://doi.org/10.3390/ijms23010422

Chicago/Turabian Style

Mashima, Emi, and Yu Sawada. 2022. "Epigenetics of Cutaneous Sarcoma" International Journal of Molecular Sciences 23, no. 1: 422. https://doi.org/10.3390/ijms23010422

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