Over Fifty Years of Life, Death, and Cannibalism: A Historical Recollection of Apoptosis and Autophagy
Abstract
:1. Brief History of Apoptosis
2. Apoptosis Induction and Regulation
2.1. Intrinsic Pathway
2.2. Extrinsic Pathway
2.2.1. Tumor Necrosis Factor Receptor (TNFR)
2.2.2. TNF-Related Apoptosis-Inducing Ligand (TRAIL)
2.2.3. Fas Receptor
3. Apoptosis in Human Diseases
4. Autophagy
5. Molecular Basis of Autophagy
6. Different Types of Autophagy
6.1. Macroautophagy
6.1.1. Initiation
6.1.2. Nucleation
6.1.3. Elongation
6.1.4. Maturation
6.1.5. Fusion
6.2. Microautophagy
6.3. Chaperone-Mediated Autophagy
7. Autophagy in Health and Disease
8. Crosstalk between Apoptosis and Autophagy
9. Conclusions
10. Materials and Methods
10.1. Developmental Apoptosis
10.2. Electron Microscopy
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Izadi, M.; Ali, T.A.; Pourkarimi, E. Over Fifty Years of Life, Death, and Cannibalism: A Historical Recollection of Apoptosis and Autophagy. Int. J. Mol. Sci. 2021, 22, 12466. https://doi.org/10.3390/ijms222212466
Izadi M, Ali TA, Pourkarimi E. Over Fifty Years of Life, Death, and Cannibalism: A Historical Recollection of Apoptosis and Autophagy. International Journal of Molecular Sciences. 2021; 22(22):12466. https://doi.org/10.3390/ijms222212466
Chicago/Turabian StyleIzadi, Mahmoud, Tayyiba Akbar Ali, and Ehsan Pourkarimi. 2021. "Over Fifty Years of Life, Death, and Cannibalism: A Historical Recollection of Apoptosis and Autophagy" International Journal of Molecular Sciences 22, no. 22: 12466. https://doi.org/10.3390/ijms222212466