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Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology

Department of Nursing, Ryazan State Medical University, 390026 Ryazan, Russia
Academic Editor: Gerhard Kostner
Int. J. Mol. Sci. 2021, 22(21), 11545; https://doi.org/10.3390/ijms222111545
Received: 30 September 2021 / Revised: 12 October 2021 / Accepted: 21 October 2021 / Published: 26 October 2021
(This article belongs to the Special Issue Atherosclerosis: Current Research of Hemodynamic and Hemorheology)
Atherosclerosis is one of the most important problems in modern medicine. Its high prevalence and social significance determine the need for a better understanding of the mechanisms of the disease’s development and progression. Lipid metabolism and its disorders are one of the key links in the pathogenesis of atherosclerosis. Lipids are involved in many processes, including those related to the mechanoreception of endothelial cells. The multifaceted role of lipids in endothelial mechanobiology and mechanisms of atherogenesis are discussed in this review. Endothelium is involved in ensuring adequate vascular hemodynamics, and changes in blood flow characteristics are detected by endothelial cells and affect their structure and function. View Full-Text
Keywords: atherosclerosis; lipid metabolism; endothelium; mechanobiology; cholesterol; plasma membrane; blood flow atherosclerosis; lipid metabolism; endothelium; mechanobiology; cholesterol; plasma membrane; blood flow
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MDPI and ACS Style

Kotlyarov, S. Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology. Int. J. Mol. Sci. 2021, 22, 11545. https://doi.org/10.3390/ijms222111545

AMA Style

Kotlyarov S. Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology. International Journal of Molecular Sciences. 2021; 22(21):11545. https://doi.org/10.3390/ijms222111545

Chicago/Turabian Style

Kotlyarov, Stanislav. 2021. "Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology" International Journal of Molecular Sciences 22, no. 21: 11545. https://doi.org/10.3390/ijms222111545

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