Next Article in Journal
Influence of Serratia marcescens and Rhodococcus rhodnii on the Humoral Immunity of Rhodnius prolixus
Next Article in Special Issue
Combined Blockade of TIGIT and CD39 or A2AR Enhances NK-92 Cell-Mediated Cytotoxicity in AML
Previous Article in Journal
Exosomes and Brain Metastases: A Review on Their Role and Potential Applications
Previous Article in Special Issue
Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 22
Issue 20
10.3390/ijms222010900
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Vaccines for Non-Viral Cancer Prevention

by
Cristina Bayó
1,
Gerhard Jung
2,
Marta Español-Rego
1,
Francesc Balaguer
2,* and
Daniel Benitez-Ribas
1,*
1
Department of Immunology, Fundació Clínic per la Recerca Biomèdica (FCRB), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain
2
Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Department of Gastroenterology, IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2021, 22(20), 10900; https://doi.org/10.3390/ijms222010900
Submission received: 9 September 2021 / Revised: 30 September 2021 / Accepted: 2 October 2021 / Published: 9 October 2021
(This article belongs to the Special Issue Immunological Approaches in Tumor Therapy)
Browse Figures
Review Reports Versions Notes

Abstract

Cancer vaccines are a type of immune therapy that seeks to modulate the host’s immune system to induce durable and protective immune responses against cancer-related antigens. The little clinical success of therapeutic cancer vaccines is generally attributed to the immunosuppressive tumor microenvironment at late-stage diseases. The administration of cancer-preventive vaccination at early stages, such as pre-malignant lesions or even in healthy individuals at high cancer risk could increase clinical efficacy by potentiating immune surveillance and pre-existing specific immune responses, thus eliminating de novo appearing lesions or maintaining equilibrium. Indeed, research focus has begun to shift to these approaches and some of them are yielding encouraging outcomes.
Keywords: vaccines; dendritic cells; cancer; prevention; Lynch syndrome vaccines; dendritic cells; cancer; prevention; Lynch syndrome

Share and Cite

MDPI and ACS Style

Bayó, C.; Jung, G.; Español-Rego, M.; Balaguer, F.; Benitez-Ribas, D. Vaccines for Non-Viral Cancer Prevention. Int. J. Mol. Sci. 2021, 22, 10900. https://doi.org/10.3390/ijms222010900

AMA Style

Bayó C, Jung G, Español-Rego M, Balaguer F, Benitez-Ribas D. Vaccines for Non-Viral Cancer Prevention. International Journal of Molecular Sciences. 2021; 22(20):10900. https://doi.org/10.3390/ijms222010900

Chicago/Turabian Style

Bayó, Cristina, Gerhard Jung, Marta Español-Rego, Francesc Balaguer, and Daniel Benitez-Ribas. 2021. "Vaccines for Non-Viral Cancer Prevention" International Journal of Molecular Sciences 22, no. 20: 10900. https://doi.org/10.3390/ijms222010900

APA Style

Bayó, C., Jung, G., Español-Rego, M., Balaguer, F., & Benitez-Ribas, D. (2021). Vaccines for Non-Viral Cancer Prevention. International Journal of Molecular Sciences, 22(20), 10900. https://doi.org/10.3390/ijms222010900

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop