Next Article in Journal
A Novel Mutation in GP1BB Reveals the Role of the Cytoplasmic Domain of GPIbβ in the Pathophysiology of Bernard-Soulier Syndrome and GPIb-IX Complex Assembly
Next Article in Special Issue
Lysophosphatidic Acid Mediates Imiquimod-Induced Psoriasis-like Symptoms by Promoting Keratinocyte Proliferation through LPAR1/ROCK2/PI3K/AKT Signaling Pathway
Previous Article in Journal
Cloning of a Passage-Free SARS-CoV-2 Genome and Mutagenesis Using Red Recombination
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 22
Issue 19
10.3390/ijms221910189
Review Report
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Article
Peer-Review Record

Proteoglycan Combined with Hyaluronic Acid and Hydrolyzed Collagen Restores the Skin Barrier in Mild Atopic Dermatitis and Dry, Eczema-Prone Skin: A Pilot Study

Int. J. Mol. Sci. 2021, 22(19), 10189; https://doi.org/10.3390/ijms221910189
by Young In Lee 1,2,†, Sang Gyu Lee 1,†, Jemin Kim 1,2, Sooyeon Choi 1, Inhee Jung 3 and Ju Hee Lee 1,2,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2021, 22(19), 10189; https://doi.org/10.3390/ijms221910189
Submission received: 23 August 2021 / Revised: 17 September 2021 / Accepted: 18 September 2021 / Published: 22 September 2021
(This article belongs to the Special Issue Functional Defects of Keratinocytes in Inflammatory Skin Diseases)

Round 1

Reviewer 1 Report

Dear authors,

The article was pleasant and easy to read.

Please find some of my comments enclosed in the pdf file.

One important comment for the soundness of the article :  In the absence of a vehicle-controlled set up in vivo, it is critical for the reader to know whether the effect is truly from the H.ECMTM liposome or something else in the cream. Even a liposome on its own would exert beneficial effect upon skin barrier, skin moisture etc...thus the title needs to highlight the exploratory nature of the study. (e.g.  Proteoglycan combined with hyaluronic acid and hydrolyzed collagen restores skin barrier in mild atopic dermatitis and dry, eczema-prone skin : a pilot study)

Then I have a question with regards to the source of the PG (salmon nasal cartilage). What was the reason for its selection ? Is it a byproduct from an industry ? It would be good to emphasize positive reason(s) for this choice, especially when considering that the plant kingdom is more appealing to consumers than fish (e.g. vegan).

Lastly, I would suggest to ask a native English speaker to have a read, to ensure some sentences read better.

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

None.

Author Response

Dear Reviewer2,

 

It is a pleasure to resubmit a revised version of our manuscript entitled “Proteoglycan combined with hyaluronic acid and hydrolyzed collagen restores the skin barrier in mild atopic dermatitis and dry, eczema-prone skin: A pilot study” for publication in the International Journal of Molecular Sciences.

 

Thank you for your input and opinion on our manuscript.

 

Thank you again for your consideration.

 

Sincerely,

 

Ju Hee Lee, M.D., Ph.D.

Department of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea

Tel: +82-2-2228-2080

Back to TopTop