Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy
Abstract
1. Introduction
2. Integrin Structure and Signaling
3. Deregulation of Integrin Signaling in Gliomas
4. Roles of Integrins and Their Ligands in Shaping A GBM Permissive Microenvironment
4.1. Cell Migration and Invasion
4.2. Crosstalk with Growth Factor Receptors
4.3. Angiogenesis
4.4. Glioma-Derived Integrin Ligands Interacting with Stromal Cells in GBM
5. Interfering with Integrin Signaling as a Therapeutic Strategy against Glioblastoma
6. Conclusions and Perspectives
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Ellert-Miklaszewska, A.; Poleszak, K.; Pasierbinska, M.; Kaminska, B. Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy. Int. J. Mol. Sci. 2020, 21, 888. https://doi.org/10.3390/ijms21030888
Ellert-Miklaszewska A, Poleszak K, Pasierbinska M, Kaminska B. Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy. International Journal of Molecular Sciences. 2020; 21(3):888. https://doi.org/10.3390/ijms21030888
Chicago/Turabian StyleEllert-Miklaszewska, Aleksandra, Katarzyna Poleszak, Maria Pasierbinska, and Bozena Kaminska. 2020. "Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy" International Journal of Molecular Sciences 21, no. 3: 888. https://doi.org/10.3390/ijms21030888
APA StyleEllert-Miklaszewska, A., Poleszak, K., Pasierbinska, M., & Kaminska, B. (2020). Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy. International Journal of Molecular Sciences, 21(3), 888. https://doi.org/10.3390/ijms21030888