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Using Probiotics as Supplementation for Helicobacter pylori Antibiotic Therapy

by and *
State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 201100, China
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(3), 1136; https://doi.org/10.3390/ijms21031136
Received: 19 December 2019 / Revised: 5 February 2020 / Accepted: 7 February 2020 / Published: 8 February 2020
(This article belongs to the Special Issue The Effect of Probiotics on Gut Homeostasis Regulation)
Helicobacter pylori is a well-known pathogen that is highly prevalent in the world population, and H. pylori infection is potentially hazardous to humans because of its relationship to various gastrointestinal diseases, such as gastric ulcers, chronic gastritis, and gastric carcinoma. Therefore, the clinical guidelines recommend taking antibiotic therapy to eradicate the pathogen, which usually leads to the desired therapeutic effect. However, some failure cases of this therapy indicate that the increasing antibiotic resistance and side effects may affect the therapeutic effect. Here we propose that using probiotics as supplementation for antibiotic therapy may provide an extra help. Recent studies have shown that probiotic supplementation therapy has promising application prospects; it can enhance the antibiotic effect to achieve a better therapeutic result and maintain the balance of the host gastrointestinal microbiota. In summary, under global conditions of increasing H. pylori prevalence, probiotic supplementation therapy is worthy of further studies for future clinical application. View Full-Text
Keywords: Helicobacter pylori; probiotic therapy; antibiotic therapy Helicobacter pylori; probiotic therapy; antibiotic therapy
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MDPI and ACS Style

Ji, J.; Yang, H. Using Probiotics as Supplementation for Helicobacter pylori Antibiotic Therapy. Int. J. Mol. Sci. 2020, 21, 1136. https://doi.org/10.3390/ijms21031136

AMA Style

Ji J, Yang H. Using Probiotics as Supplementation for Helicobacter pylori Antibiotic Therapy. International Journal of Molecular Sciences. 2020; 21(3):1136. https://doi.org/10.3390/ijms21031136

Chicago/Turabian Style

Ji, Jianfu; Yang, Hong. 2020. "Using Probiotics as Supplementation for Helicobacter pylori Antibiotic Therapy" Int. J. Mol. Sci. 21, no. 3: 1136. https://doi.org/10.3390/ijms21031136

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