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The Current Status of Drug Repositioning and Vaccine Developments for the COVID-19 Pandemic

by 1,2 and 1,2,3,4,5,*
1
Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea
2
Center for Convergence Approaches in Drug Development, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea
3
Department of Clinical Pharmacology and Therapeutics, College of Medicine, Seoul National University, Seoul 03080, Korea
4
Department of Clinical Pharmacology and Therapeutics, Seoul National University Hospital, Seoul 03080, Korea
5
Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 16229, Korea
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(24), 9775; https://doi.org/10.3390/ijms21249775
Received: 30 November 2020 / Revised: 15 December 2020 / Accepted: 18 December 2020 / Published: 21 December 2020
(This article belongs to the Section Molecular Pharmacology)
Since the outbreak of coronavirus disease 2019 (COVID-19) was first identified, the world has vehemently worked to develop treatments and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented speed. Few of the repositioned drugs for COVID-19 have shown that they were efficacious and safe. In contrast, a couple of vaccines against SARS-CoV-2 will be ready for mass rollout early next year. Despite successful vaccine development for COVID-19, the world will face a whole new set of challenges including scale-up manufacturing, cold-chain logistics, long-term safety, and low vaccine acceptance. We highlighted the importance of knowledge sharing and collaboration to find innovative answers to these challenges and to prepare for newly emerging viruses. View Full-Text
Keywords: SARS-CoV-2; COVID-19; drug repositioning; vaccine; public health crisis SARS-CoV-2; COVID-19; drug repositioning; vaccine; public health crisis
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MDPI and ACS Style

Won, J.-H.; Lee, H. The Current Status of Drug Repositioning and Vaccine Developments for the COVID-19 Pandemic. Int. J. Mol. Sci. 2020, 21, 9775. https://doi.org/10.3390/ijms21249775

AMA Style

Won J-H, Lee H. The Current Status of Drug Repositioning and Vaccine Developments for the COVID-19 Pandemic. International Journal of Molecular Sciences. 2020; 21(24):9775. https://doi.org/10.3390/ijms21249775

Chicago/Turabian Style

Won, Jung-Hyun, and Howard Lee. 2020. "The Current Status of Drug Repositioning and Vaccine Developments for the COVID-19 Pandemic" International Journal of Molecular Sciences 21, no. 24: 9775. https://doi.org/10.3390/ijms21249775

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