Dendritic Cells: Critical Regulators of Allergic Asthma
Abstract
:1. Introduction
2. DC Subsets and Their Role in the Regulation of Allergic Asthma
2.1. Allergic Asthma
2.2. Innate and Adaptive Immune Responses in Lung Allergic Inflammation
2.3. Localization and Phenotype of DC Subsets in the Lung
2.4. The Role of Murine DCs in the Induction of Allergic Responses in Asthma
2.5. The Role of Human DC Subsets in Shaping Asthmatic Responses
2.6. The Role of Tolerogenic DCs in the Resolution of Allergic Airway Inflammation in the Airways
2.7. A Novel Subset of Tolerogenic DCs Confers Protection against Experimental Asthma
3. Conclusions
Author Contributions
Funding
Conflicts of Interest
Abbreviations
AHR | airway hyperresponsiveness |
Bte | Blomia tropicalis mite |
cDCs | conventional DCs |
cDCs1 | cDCs type 1 |
cDCs2 | cDCs type 2 |
DCs | dendritic cells |
Der p1 | Dermatophagoides pteronyssinus antigen P1 |
FlaB | flagellin-B |
HDM | house dust mite |
MLNs | mediastinal lymph nodes |
mo-DCs | monocyte-derived DCs |
mDCs | myeloid DCs |
Ova | ovalbumin |
PB | peripheral blood |
pDCs | plasmacytoid DCs |
Th | T helper |
TFH | T follicular helper |
Treg | Regulatory T cell |
TSLP | Thymic stromal lymphopoietin |
WT | wild type |
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Morianos, I.; Semitekolou, M. Dendritic Cells: Critical Regulators of Allergic Asthma. Int. J. Mol. Sci. 2020, 21, 7930. https://doi.org/10.3390/ijms21217930
Morianos I, Semitekolou M. Dendritic Cells: Critical Regulators of Allergic Asthma. International Journal of Molecular Sciences. 2020; 21(21):7930. https://doi.org/10.3390/ijms21217930
Chicago/Turabian StyleMorianos, Ioannis, and Maria Semitekolou. 2020. "Dendritic Cells: Critical Regulators of Allergic Asthma" International Journal of Molecular Sciences 21, no. 21: 7930. https://doi.org/10.3390/ijms21217930