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Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications

Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland
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Int. J. Mol. Sci. 2020, 21(19), 7078; https://doi.org/10.3390/ijms21197078
Received: 29 August 2020 / Revised: 22 September 2020 / Accepted: 23 September 2020 / Published: 25 September 2020
(This article belongs to the Special Issue Terpenes and Essential Oils: Health Risks and Benefits)
Monoterpenes, comprising hydrocarbons, are the largest class of plant secondary metabolites and are commonly found in essential oils. Monoterpenes and their derivatives are key ingredients in the design and production of new biologically active compounds. This review focuses on selected aliphatic, monocyclic, and bicyclic monoterpenes like geraniol, thymol, myrtenal, pinene, camphor, borneol, and their modified structures. The compounds in question play a pivotal role in biological and medical applications. The review also discusses anti-inflammatory, antimicrobial, anticonvulsant, analgesic, antiviral, anticancer, antituberculosis, and antioxidant biological activities exhibited by monoterpenes and their derivatives. Particular attention is paid to the link between biological activity and the effect of structural modification of monoterpenes and monoterpenoids, as well as the introduction of various functionalized moieties into the molecules in question. View Full-Text
Keywords: geraniol; thymol; myrtenal; pinene; camphor; borneol; biological activity; antiviral activity; analgesic activity; anti-inflammatory activity geraniol; thymol; myrtenal; pinene; camphor; borneol; biological activity; antiviral activity; analgesic activity; anti-inflammatory activity
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MDPI and ACS Style

Zielińska-Błajet, M.; Feder-Kubis, J. Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications. Int. J. Mol. Sci. 2020, 21, 7078. https://doi.org/10.3390/ijms21197078

AMA Style

Zielińska-Błajet M, Feder-Kubis J. Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications. International Journal of Molecular Sciences. 2020; 21(19):7078. https://doi.org/10.3390/ijms21197078

Chicago/Turabian Style

Zielińska-Błajet, Mariola, and Joanna Feder-Kubis. 2020. "Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications" International Journal of Molecular Sciences 21, no. 19: 7078. https://doi.org/10.3390/ijms21197078

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